ID G1U4V2_RABIT Unreviewed; 304 AA.
AC G1U4V2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000024427.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000024427.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000024427.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000024427.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR AlphaFoldDB; G1U4V2; -.
DR SMR; G1U4V2; -.
DR STRING; 9986.ENSOCUP00000024427; -.
DR PaxDb; 9986-ENSOCUP00000024427; -.
DR Ensembl; ENSOCUT00000031355.3; ENSOCUP00000024427.2; ENSOCUG00000026191.3.
DR eggNOG; KOG1584; Eukaryota.
DR GeneTree; ENSGT00940000163403; -.
DR HOGENOM; CLU_027239_1_0_1; -.
DR InParanoid; G1U4V2; -.
DR OMA; ECPPESC; -.
DR TreeFam; TF321745; -.
DR Proteomes; UP000001811; Unplaced.
DR Bgee; ENSOCUG00000026191; Expressed in ovary and 8 other cell types or tissues.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF212; SULFOTRANSFERASE; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT DOMAIN 49..295
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 304 AA; 35022 MW; CF9B5EBA0B5FB42D CRC64;
MPRLSAGTEP RASMSRDLDS VEVFDGICFP GYLHSPESLQ AACAFQFQDT DVLLATFPKS
GTTWMQQILS LIFCEGDLRP IHHCPSWARM PWLEHISFQG FLAQMDPARP RLLTTHLQAR
ALAPALKKSN ARVVYVARHP KDVLVSFYHF HRMASFLPDP SSFQDFVDKF LEGKGFYNSW
FDHVKEWLSL LQDLNMLFVT YEELHQEPRR ALRKLSEFLG RPLGVQEEDL ILGHSSFSFM
RQSRAANYSL VPREIMDPAR SPFLRKGVVG DWQEHFTPEQ NEKFNAVYQA KMSDCSVCLP
WSMD
//
