ID   G1U6I6_RABIT            Unreviewed;       432 AA.
AC   G1U6I6;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Acyl-CoA thioesterase 4 {ECO:0000313|Ensembl:ENSOCUP00000025031.2};
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000025031.2, ECO:0000313|Proteomes:UP000001811};
RN   [1] {ECO:0000313|Ensembl:ENSOCUP00000025031.2, ECO:0000313|Proteomes:UP000001811}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000025031.2,
RC   ECO:0000313|Proteomes:UP000001811};
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA   Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA   Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA   Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA   Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA   Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA   Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA   Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA   Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA   Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA   Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA   Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA   Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA   Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA   Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL   Nature 478:476-482(2011).
RN   [2] {ECO:0000313|Ensembl:ENSOCUP00000025031.2}
RP   IDENTIFICATION.
RC   STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000025031.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AAGW02049260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGW02049261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGW02049262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; G1U6I6; -.
DR   Ensembl; ENSOCUT00000026777.2; ENSOCUP00000025031.2; ENSOCUG00000022543.3.
DR   eggNOG; ENOG502QQ8Z; Eukaryota.
DR   GeneTree; ENSGT01010000222336; -.
DR   HOGENOM; CLU_029849_4_0_1; -.
DR   TreeFam; TF314911; -.
DR   Proteomes; UP000001811; Chromosome 20.
DR   Bgee; ENSOCUG00000022543; Expressed in liver and 17 other cell types or tissues.
DR   ExpressionAtlas; G1U6I6; baseline.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR014940; BAAT_C.
DR   PANTHER; PTHR10824:SF16; ACYL-COENZYME A THIOESTERASE 1-RELATED; 1.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   Pfam; PF08840; BAAT_C; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT   DOMAIN          44..171
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   DOMAIN          222..429
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
SQ   SEQUENCE   432 AA;  46892 MW;  E97EC08D61FA9BA0 CRC64;
     MDIFGVGGGL LEYRASLLAG KGFAVMALAY YNYDDLPKSM DTLHLEYFEE AVNYLISRPE
     VKGPGIGLLG HSKGGELCLT MTSFLKGITA AVIINGSIAN VGGTLRYKDM TLPPIGANRS
     RIKMTKEGFA DIVDALNSPL EGPDQKSLIP VERSECTFLF LVGQDDHNWK SPGPFPGIVD
     MFGVGGGLLE YRASLLAGKG FAVMALAYYN YDDLPKSMDT LHLEYFEEAV NYLISRPEVK
     GPGIGLLGHS KGGELGLTMT SFLKGITAAV IINGSIVNVG GTLHYKDVTL PPIGANRSRI
     KMTKEGFADI VDALNSPLEG PDQKSLIPVE RSECTFLFLV GQDDHNWKSE FYANEASKRL
     QAQGKAKPQI ICYPEAGHYI EPPYFPLCRA SLHALVGGPV FWGGEPRAHA VAQVDAWKQL
     QTFFHKHLGG ES
//