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Database: UniProt
Entry: G1Y038_9PROT
LinkDB: G1Y038_9PROT
Original site: G1Y038_9PROT 
ID   G1Y038_9PROT            Unreviewed;       505 AA.
AC   G1Y038;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   05-JUL-2017, entry version 38.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AZA_17588 {ECO:0000313|EMBL:EGY01120.1};
OS   Nitrospirillum amazonense Y2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Nitrospirillum.
OX   NCBI_TaxID=1003237 {ECO:0000313|EMBL:EGY01120.1, ECO:0000313|Proteomes:UP000018435};
RN   [1] {ECO:0000313|EMBL:EGY01120.1, ECO:0000313|Proteomes:UP000018435}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y2 (ATCC 35120) {ECO:0000313|Proteomes:UP000018435};
RX   PubMed=21838888; DOI=10.1186/1471-2164-12-409;
RA   Sant'anna F.H., Almeida L.G., Cecagno R., Reolon L.A., Siqueira F.M.,
RA   Machado M.R., Vasconcelos A.T., Schrank I.S.;
RT   "Genomic insights into the versatility of the plant growth-promoting
RT   bacterium Azospirillum amazonense.";
RL   BMC Genomics 12:409-409(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EGY01120.1}.
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DR   EMBL; AFBX01000464; EGY01120.1; -; Genomic_DNA.
DR   RefSeq; WP_004272982.1; NZ_AFBX01000464.1.
DR   EnsemblBacteria; EGY01120; EGY01120; AZA_17588.
DR   PATRIC; fig|1003237.3.peg.2736; -.
DR   Proteomes; UP000018435; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018435};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018435}.
FT   DOMAIN      202    330       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      413    482       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     210    217       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   505 AA;  56297 MW;  995AF17C3C5F1361 CRC64;
     MSVQASLDQQ WARISGRLKD EVGETAYRSW LKPLTVEDFI GGQVRIVVPT RFMRDWIRTH
     YADRIRALWT GENPGVQSVE IVVAPPRNDA SLGGALTTGP RAAANAIADA GLLAETGIDH
     LPTYGEVQAS ASLNGGLHGG LNGVAEAPAL PAFIAGNGLG EERDDVSALL DPRFTFENFV
     VGKPNELAFA AARRVADANA VTFNPLFLYG GVGLGKTHLM HAIAWHIRKK DPARRVIYLS
     AEKFMYQFIR ALRYKDTMAF KEQFRSVDVL MIDDVQFISG KDSTQEEFFH TFNALVDQNR
     QVIISADKSP SDLEGMEERL RSRLGWGLVA DIHPTTYELR LGILQSKGEQ MRVQIPQKVL
     EFLAHKITSN VRELEGALNR IVAHAELVGR AITLESSQEV LHDLLRASNR RVTIEEIQKK
     VAEHYNIRLA DMSSARRARA VARPRQVAMY LSKQLTARSL PEIGRKFGDR DHTTVMHAVR
     KVEELCATDP TFSEDVELLR RMLEG
//
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