ID G2FFM7_9GAMM Unreviewed; 953 AA.
AC G2FFM7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S) {ECO:0000313|EMBL:EGW54443.1};
GN ORFNames=TevJSym_am00750 {ECO:0000313|EMBL:EGW54443.1};
OS endosymbiont of Tevnia jerichonana (vent Tica).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; sulfur-oxidizing symbionts.
OX NCBI_TaxID=1049564 {ECO:0000313|EMBL:EGW54443.1, ECO:0000313|Proteomes:UP000005167};
RN [1] {ECO:0000313|EMBL:EGW54443.1, ECO:0000313|Proteomes:UP000005167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Gardebrecht A., Markert S., Felbeck H., Thuermer A., Albrecht D.,
RA Wollherr A., Kabisch J., Lehmann R., Daniel R., Liesegang H., Hecker M.,
RA Sievert S.M., Schweder T.;
RT "The endosymbionts of the deep-sea tubeworms Riftia pachyptila and Tevnia
RT jerichonana share an identical physiology as revealed by proteogenomic
RT analyses.";
RL ISME J. 0:0-0(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGW54443.1}.
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DR EMBL; AFZB01000013; EGW54443.1; -; Genomic_DNA.
DR RefSeq; WP_005959777.1; NZ_AFZB01000013.1.
DR AlphaFoldDB; G2FFM7; -.
DR PATRIC; fig|1049564.3.peg.1713; -.
DR eggNOG; COG5001; Bacteria.
DR Proteomes; UP000005167; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR029150; dCache_3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF14827; dCache_3; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005167};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 302..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..528
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 560..693
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 704..953
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 953 AA; 106054 MW; 77EBA58235150C99 CRC64;
MAGQAKESAR FFSLKWKAGL LFSLILIGVN GGLAALGYLQ LQHQFVQHQR EINQQQAEEL
RALVLDRFQQ LEQVAALTPV IAASQSGESR LAKRLEMVFE QNAATLEIDW GLDFAAFFSS
SGEPLYHWQS EQTLAYFKPQ VAQVNRTQQP FHWIDCQRGC RQFVAEPLLD RAEYAGVTLL
GRPISDLILA FNSITGADIA LLSQSAQPGP DPLAGTLAAH WGVGVVARSQ ADQLLPMLNA
AASRIALTQL QEEPQQLTYA GNRYALQIVP LSASSGVHRP QFLIINDITR SVEQIEHSIR
TAVIAGLLGL LLSEAVLLLL LWSPMRRLRL LSRALPLLAQ NAFAEVQHKL ARPIKWIAAD
EIDVAGGAVL DLAARLEALN LEVRKRAISL IERSEELARE RDFVTSLLHN AQVVILTQGS
QGQLLSINPE GERVFGCREE QAGKLSFLEL IEVAGEMDDP EPYLQRLKRG EIDVYQHDSR
VVSDDGRQFS ISWVHSRLPA KDADDLPLLL SIGLDVTERK VAERNLAWLA DHDPLTELFN
RRRLVAELER LLERSERYDE SGALLFIDLD QFKYVNDISG HQAGDALLKI IARQLAQATR
SSDILARIGG DEFAMLLPNA DVSAAVDVAG KLLDVMKGIE LPSKEASQRI SASIGVVLFP
DHGVNLQDLM ANADLAMYQA KERGRDRWHL FAQDEQIREQ MSDSVSLKGK IEWALAEGGF
LLHYQPIMEI ASRRISHYEV LLRLREADAR IVMPGDFIPV AEKTGLIHSI DRLVLREAIN
RLAELGKAGQ QLINLSVNLS GWAVDDPELL PLLKQLLQLR GVRPQQLVFE ITETAALADM
AAAESFIREL QELGCRFAMD DFGVGFSSFY YLRELPLDIV KIDGSFIRQL PQNRKDQVFV
KALVEMASGL GKKTIAEFVE DEATLHMLEE IGVDYAQGYF IGRPQAEIEL PTG
//
