ID G2H1E2_9ENTR Unreviewed; 115 AA.
AC G2H1E2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Cell division protein ZapA {ECO:0000256|ARBA:ARBA00015195};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000256|ARBA:ARBA00033158};
GN ORFNames=Rin_00018840 {ECO:0000313|EMBL:EGY28177.1};
OS Candidatus Regiella insecticola 5.15.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Candidatus Regiella.
OX NCBI_TaxID=1005043 {ECO:0000313|EMBL:EGY28177.1, ECO:0000313|Proteomes:UP000004116};
RN [1] {ECO:0000313|EMBL:EGY28177.1, ECO:0000313|Proteomes:UP000004116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R5.15 {ECO:0000313|Proteomes:UP000004116};
RX PubMed=21948522; DOI=10.1101/gr.125351.111;
RA Hansen A.K., Vorburger C., Moran N.A.;
RT "Genomic basis of endosymbiont-conferred protection against an insect
RT parasitoid.";
RL Genome Res. 22:106-114(2012).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000256|ARBA:ARBA00024910}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ.
CC {ECO:0000256|ARBA:ARBA00026068}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC {ECO:0000256|ARBA:ARBA00010074}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGY28177.1}.
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DR EMBL; AGCA01000443; EGY28177.1; -; Genomic_DNA.
DR RefSeq; WP_006707522.1; NZ_AGCA01000443.1.
DR AlphaFoldDB; G2H1E2; -.
DR PATRIC; fig|1005043.3.peg.1741; -.
DR OrthoDB; 5917174at2; -.
DR Proteomes; UP000004116; Unassembled WGS sequence.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.50; -; 1.
DR Gene3D; 3.30.160.880; Cell division protein ZapA protomer, N-terminal domain; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR042233; Cell_div_ZapA_N.
DR PANTHER; PTHR34981; CELL DIVISION PROTEIN ZAPA; 1.
DR PANTHER; PTHR34981:SF1; CELL DIVISION PROTEIN ZAPA; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; Cell division protein ZapA-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000004116};
KW Septation {ECO:0000256|ARBA:ARBA00023210}.
FT COILED 24..51
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 115 AA; 13104 MW; F2BA13A8C4F49B6D CRC64;
MSAQPVDIQI FGRSLRVNCP PEQQDALNTA AADLEQRLHD LKNRTKVNKT ECLALTAALN
LCHELAQQTK KMREENIKKA EFLNKMEQRI RLLQQVIEQA LPNQNCIAES LEHAT
//