ID G2HJ53_PANTR Unreviewed; 87 AA.
AC G2HJ53;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Pepsin A {ECO:0000313|EMBL:BAK63761.1};
GN Name=LOC107973353 {ECO:0000313|Ensembl:ENSPTRP00000074928.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:BAK63761.1};
RN [1] {ECO:0000313|EMBL:BAK63761.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Testis {ECO:0000313|EMBL:BAK63761.1};
RX PubMed=21484476; DOI=10.1007/s10142-011-0220-9;
RA Kim R.N., Kim D.W., Choi S.H., Chae S.H., Nam S.H., Kim D.W., Kim A.,
RA Kang A., Park K.H., Lee Y.S., Hirai M., Suzuki Y., Sugano S., Hashimoto K.,
RA Kim D.S., Park H.S.;
RT "Major chimpanzee-specific structural changes in sperm development-
RT associated genes.";
RL Funct. Integr. Genomics 11:507-517(2011).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000074928.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447}.
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DR EMBL; AK306767; BAK63761.1; -; mRNA.
DR RefSeq; XP_016803577.1; XM_016948088.1.
DR MEROPS; A01.001; -.
DR PaxDb; 9598-ENSPTRP00000061179; -.
DR Ensembl; ENSPTRT00000103020.1; ENSPTRP00000074928.1; ENSPTRG00000045729.1.
DR GeneTree; ENSGT00940000155036; -.
DR OMA; TICAKHI; -.
DR Proteomes; UP000002277; Unplaced.
DR Bgee; ENSPTRG00000045729; Expressed in temporal lobe and 1 other cell type or tissue.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR47966:SF22; PEPSIN A-3-RELATED; 1.
DR Pfam; PF00026; Asp; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 1..87
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
SQ SEQUENCE 87 AA; 9051 MW; BF19AA2284E14A4E CRC64;
MNGEAIACAE GCQAIVDTGT SLLTGPTSPI ANIQSDIGAS ENSDGDMVVS CSAISSLPDI
VFTINGVQYP VPPSAYILQV RRLWTNH
//
