ID G2J1U3_PSEUL Unreviewed; 315 AA.
AC G2J1U3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Dihydrodipicolinate synthase {ECO:0000313|EMBL:BAK76271.1};
GN OrderedLocusNames=NH8B_1449 {ECO:0000313|EMBL:BAK76271.1};
OS Pseudogulbenkiania sp. (strain NH8B).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chromobacteriaceae; Pseudogulbenkiania.
OX NCBI_TaxID=748280 {ECO:0000313|EMBL:BAK76271.1, ECO:0000313|Proteomes:UP000001274};
RN [1] {ECO:0000313|Proteomes:UP000001274}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NH8B {ECO:0000313|Proteomes:UP000001274};
RX PubMed=22038961; DOI=10.1128/JB.06127-11;
RA Ishii S., Tago T., Nishizawa T., Oshima K., Hattori M., Senoo K.;
RT "Complete genome sequence of the denitrifying and N(2)O-reducing bacterium
RT Pseudogulbenkiania sp. strain NH8B.";
RL J. Bacteriol. 193:6395-6396(2011).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; AP012224; BAK76271.1; -; Genomic_DNA.
DR RefSeq; WP_014086655.1; NC_016002.1.
DR AlphaFoldDB; G2J1U3; -.
DR STRING; 748280.NH8B_1449; -.
DR KEGG; pse:NH8B_1449; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_075248_0_0_4; -.
DR OrthoDB; 9782828at2; -.
DR Proteomes; UP000001274; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000001274}.
FT ACT_SITE 136
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 164
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 209
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 315 AA; 33947 MW; FDBC09F2A446B132 CRC64;
MSDNIFTGCI PALMTPCTAD RKPDFDALVA KGRELIEIGM SAVVYCGSMG DWPLLTEAER
QEGVARLVAA GIPTIVGTGA VNTREAVSHA AHAAKVGAHG LMVIPRVLSR GASPAAQKAH
FAAILKAAPG LPAVIYNSPY YGFATRADLF FELRRDYPNL IGFKEFGGGA DLRYAAENIT
SKDDEITLMV GVDTQVVHGF VNCNATGAIT GIGNVLPREV LQLVALSKQA AKGDAKARRL
AGELESALAV LSSFDEGCDL VLYYKHLMVL NGDKEYTLHF NESDVLSDAQ RRYAENQYAL
FREWYGNWSA EQNVA
//
