ID G2MXN8_9THEO Unreviewed; 432 AA.
AC G2MXN8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=Thewi_1885 {ECO:0000313|EMBL:AEM79268.1};
OS Thermoanaerobacter wiegelii Rt8.B1.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=697303 {ECO:0000313|EMBL:AEM79268.1, ECO:0000313|Proteomes:UP000008276};
RN [1] {ECO:0000313|EMBL:AEM79268.1, ECO:0000313|Proteomes:UP000008276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rt8.B1 {ECO:0000313|EMBL:AEM79268.1,
RC ECO:0000313|Proteomes:UP000008276};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Daligault H., Detter J.C., Han C.,
RA Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hemme C.,
RA Woyke T.;
RT "Complete sequence of Thermoanaerobacter wiegelii Rt8.B1.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP002991; AEM79268.1; -; Genomic_DNA.
DR RefSeq; WP_014063232.1; NC_015958.1.
DR AlphaFoldDB; G2MXN8; -.
DR STRING; 697303.Thewi_1885; -.
DR KEGG; twi:Thewi_1885; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_634495_0_0_9; -.
DR Proteomes; UP000008276; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 2.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:AEM79268.1};
KW Cilium {ECO:0000313|EMBL:AEM79268.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:AEM79268.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 50..128
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 239..311
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT DOMAIN 323..386
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 432 AA; 46731 MW; 480D1C5877A8BEF2 CRC64;
MASLIDTNYW YMYPYYSEYS YLFNMTNPLT SIQNITPSNI FEIAQQAMYI NNENQQLPTQ
ITNVLVMLNS YANNLAETAT QLQLTSPNSV FNQMIATSSD PNSISATAQA GATASTYNVS
VNQLAVAQQN IGTSLASNSI TSLTPGTYSF TVQVGGKQYN ISFNVNQGDT NQTVLNNMAQ
AINFANIGIT AIVNNDPYLG TSQLVLNANS TGTNNAFTLT DVTGNAVSYT GANTVSVAAA
NATYAINGIS NTSQSNTIYL DNNNLAITFN KTVSNVTVTV THDIQAISNS INNFVNEYNK
IITYINQNQQ YISPIVTSEL VQSYEYQAAN LQAIGITQNP DMTLSIDQNT LNNALQNNFN
TVQTAFAGYN GLAVNVGQIA EQIAESPLTA YANEMVPIGN NYMGLYNSLG MLDTSLIWSM
LLPSGQFVNS FI
//
