ID G2NM24_STREK Unreviewed; 507 AA.
AC G2NM24;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SACTE_4471 {ECO:0000313|EMBL:AEN12301.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN12301.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN12301.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN12301.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; CP002993; AEN12301.1; -; Genomic_DNA.
DR RefSeq; WP_014048259.1; NC_015953.1.
DR AlphaFoldDB; G2NM24; -.
DR STRING; 862751.SACTE_4471; -.
DR KEGG; ssx:SACTE_4471; -.
DR PATRIC; fig|862751.12.peg.4642; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_008392_5_3_11; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF15; BETA-HEXOSAMINIDASE LPQI; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AEN12301.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001397}.
FT DOMAIN 40..329
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT REGION 339..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 52024 MW; ED64D89E6EA2590E CRC64;
MTTLVSTTDT VTRDALAVLQ PGFTGTTAPD WLLRRVGEGL ASVGLFGRNI HSPEQLAALT
ARLRAERDDV LVAIDEEGGD VTRLEVRDGS SFPGNLALGS VDDVELTRAV AQELGRRLAE
CGVNLNWAPS ADVNSNPGNP VIGVRSFGAD PDLVARHTAA YVQGLQASGV AACTKHFPGH
GDTAVDSHLA LPSIEVDLET LHARELVPFR AAIAAGSKSV MSAHILLPAL DAARPATLSP
QILTGLLRQE LGYEGLIVTD GMEMDAIAGT YGIERGSVLA IAAGADAICV GGGLADEDTV
LLLRDALVAA VRSGDLPEER LADAAARVRA LASWTQRARG AGSEPGAAVQ EGTAPGTGVS
SDIGLAAARR ALRSTGTAAP QTEPVYVAAF TPVANIAVGA ETPWGVAAEL ERLLPGTATG
TYGGAEVEAV LRAAGERRVV AVVRDEHRHP WMGEALDGLL AARPDTVVVE MGLPEAPARG
ALHIATYGAA RVCGAAAAEA ITGARTA
//
