ID G2NNB8_STREK Unreviewed; 857 AA.
AC G2NNB8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=DEAD/DEAH box helicase domain protein {ECO:0000313|EMBL:AEN08549.1};
GN ORFNames=SACTE_0612 {ECO:0000313|EMBL:AEN08549.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN08549.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN08549.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN08549.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|ARBA:ARBA00008708}.
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DR EMBL; CP002993; AEN08549.1; -; Genomic_DNA.
DR AlphaFoldDB; G2NNB8; -.
DR STRING; 862751.SACTE_0612; -.
DR KEGG; ssx:SACTE_0612; -.
DR PATRIC; fig|862751.12.peg.656; -.
DR eggNOG; COG4581; Bacteria.
DR HOGENOM; CLU_017075_0_0_11; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR021904; DUF3516.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF12029; DUF3516; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AEN08549.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001397}.
FT DOMAIN 59..215
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 274..439
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 857 AA; 95296 MW; AB55941F20E8F040 CRC64;
MIFARSAGSL IGTWGRQDGG VTLIDQLPPT ADPDALFEAF SSWTESQGIT LYPAQEEALI
EVVSGANVIL STPTGSGKSL VAAGAHFTAL AQDKVTFYTA PIKALVSEKF FDLCKLFGTE
NVGMLTGDAS VNADAPVICC TAEVLASIAL RDGRYADIGQ VVMDEFHFYA EPDRGWAWQI
PLLELPQAQF VLMSATLGDV SMFEEDLTRR TGRPTSVVRS ATRPVPLSYE YRLTPITETL
TELLDTRQSP VYIVHFTQAA AVERAQSLMS INMCTKEEKE KIADLIGSFR FTTKFGQNLS
RYVRHGIGVH HAGMLPKYRR LVEKLAQAGL LKVICGTDTL GVGVNVPIRT VLFTALTKYD
GTRVRTLRAR EFHQIAGRAG RAGFDTAGFV VAQAPEHVIE NEKAVKKAGD DPKKKRKVVR
KKAPEGFVAW SETTFDKLIQ SEPEPLTSRF RVTHTMLLSV IARPGNAFEA MRHLLEDNHE
PRRAQLRHIR RAIAIYRSLL DGGVVEQLET PDAEGRIVRL TVDLQQDFAL NQPLSTFALA
AFDLLDAESP SYALDMVSVV ESTLDDPRQI LAAQQNKARG EAVGQMKADG VEYEERMERL
QEVTYPKPLS ELLWHAYDVY RTSHPWVGDH PVSPKSVVRD MYERAMTFTE FTSNYELART
EGIVLRYLAS AYKALEHTVP DDLKSEDLQD LIAWLGELVR QVDSSLLDEW EQLANPEVET
AEQAQERADE VKPVTANSRA FRVLVRNAMF RRVELAALDR VRDLGELDAG SGWDEDAWGE
AMDAYWDAHE DLGTGPDARG PKLLKIEEDP EHGLWRVWQA FADPAGDHDW GIRAEVDLAA
SDEEGRAVVR VTQVGQL
//
