ID G2NRT2_STREK Unreviewed; 318 AA.
AC G2NRT2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:AEN08704.1};
GN ORFNames=SACTE_0775 {ECO:0000313|EMBL:AEN08704.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN08704.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN08704.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN08704.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP002993; AEN08704.1; -; Genomic_DNA.
DR RefSeq; WP_014044696.1; NC_015953.1.
DR AlphaFoldDB; G2NRT2; -.
DR STRING; 862751.SACTE_0775; -.
DR KEGG; ssx:SACTE_0775; -.
DR PATRIC; fig|862751.12.peg.820; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_11; -.
DR OrthoDB; 3505530at2; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08423; PBP2_LTTR_like_6; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001397}.
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
FT REGION 297..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 34327 MW; C0234CCF9873D27E CRC64;
MLNLERLRTL DALARHGSVS GAADGLHVTT SAVSQQMSKL EREVGQRLLA RNGRGVRLTD
AGRLLADHAA RILSQVELAQ SDIEAQRGEV VGEVRLAAFP TAARGLFPAA LTTLRADHPE
LTLRTTELEP EAGIRAVLRG DVDLAVVLDW SNKRLPVPGG LTKAELLEDA PDIAMPADHP
LAERAEVGLE DFADDDWVSW PEGEFCHDWL MFTLRSKGIE PRIAHLAGEH HTQLALIAAG
FGVCVAPRLG RGPVPEGLRL VPVRQTMRRH VHAVWRTDAD RRPSIRAAVS ALRAAGRALH
EPAPAGAPDG SGERAELP
//
