ID   G2T4D2_ROSHA            Unreviewed;       253 AA.
AC   G2T4D2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase {ECO:0000313|EMBL:AEN97737.1};
DE            EC=2.3.1.157 {ECO:0000313|EMBL:AEN97737.1};
GN   Name=glmU {ECO:0000313|EMBL:AEN97737.1};
GN   OrderedLocusNames=RHOM_13145 {ECO:0000313|EMBL:AEN97737.1};
OS   Roseburia hominis (strain DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=585394 {ECO:0000313|EMBL:AEN97737.1, ECO:0000313|Proteomes:UP000008178};
RN   [1] {ECO:0000313|EMBL:AEN97737.1, ECO:0000313|Proteomes:UP000008178}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183
RC   {ECO:0000313|Proteomes:UP000008178};
RX   PubMed=26543119; DOI=10.1128/genomeA.01286-15;
RA   Travis A.J., Kelly D., Flint H.J., Aminov R.I.;
RT   "Complete genome sequence of the human gut symbiont Roseburia hominis.";
RL   Genome Announc. 3:E0128615-E0128615(2015).
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DR   EMBL; CP003040; AEN97737.1; -; Genomic_DNA.
DR   RefSeq; WP_014080743.1; NC_015977.1.
DR   AlphaFoldDB; G2T4D2; -.
DR   STRING; 585394.RHOM_13145; -.
DR   GeneID; 77460183; -.
DR   KEGG; rho:RHOM_13145; -.
DR   eggNOG; COG1207; Bacteria.
DR   HOGENOM; CLU_029499_15_0_9; -.
DR   OrthoDB; 9775031at2; -.
DR   BioCyc; RHOM585394:G1H02-2611-MONOMER; -.
DR   Proteomes; UP000008178; Chromosome.
DR   GO; GO:0019134; F:glucosamine-1-phosphate N-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd02540; GT2_GlmU_N_bac; 1.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR43584:SF3; BIFUNCTIONAL PROTEIN GLMU; 1.
DR   PANTHER; PTHR43584; NUCLEOTIDYL TRANSFERASE; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000313|EMBL:AEN97737.1};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008178};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEN97737.1}.
FT   DOMAIN          5..212
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
SQ   SEQUENCE   253 AA;  27662 MW;  8CC9B9D16F55A391 CRC64;
     MSQLKAVILA AGKGTRMKSD LPKVVHTIEG KCLVDYAIEA AEGAGAGEIC LVVGYKYEIV
     RESISHKDVK FVLQEQQLGT GHAVRCAKEF LGEEGQTLIL FGDTPLITAE TLKKLREHHI
     ASGNTVTVLS AMVEDPTGYG RIIRDADGNF VKSVEHKDAT EAELASHEIN SGMYIFDTKE
     LREALDLILP NNAQGEYYLP DTLTIIKEKG LKVDAYALDD PEDITGVNDQ EQLAAAAVVI
     RRRIAGNKAK NRR
//