ID G2WZP4_VERDV Unreviewed; 357 AA.
AC G2WZP4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=TOXD protein {ECO:0000313|EMBL:EGY22046.1};
GN ORFNames=VDAG_03486 {ECO:0000313|EMBL:EGY22046.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY22046.1, ECO:0000313|Proteomes:UP000001611};
RN [1] {ECO:0000313|Proteomes:UP000001611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC {ECO:0000313|Proteomes:UP000001611};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; DS572699; EGY22046.1; -; Genomic_DNA.
DR RefSeq; XP_009655646.1; XM_009657351.1.
DR AlphaFoldDB; G2WZP4; -.
DR STRING; 498257.G2WZP4; -.
DR EnsemblFungi; EGY22046; EGY22046; VDAG_03486.
DR GeneID; 20704949; -.
DR KEGG; vda:VDAG_03486; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_026673_16_1_1; -.
DR InParanoid; G2WZP4; -.
DR OMA; GPKFEAK; -.
DR OrthoDB; 2267374at2759; -.
DR Proteomes; UP000001611; Chromosome 6.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001611}.
FT DOMAIN 28..355
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 357 AA; 37742 MW; 424082FDBE246D8C CRC64;
MKALVSNRFI ASRLFNLAFN KSIFTPGGSV IEVPKPTIGA NEILVKVKAV ALNPTDFKHL
DIISPPGSII GCDYAGEVAE VGSNATALWK VGDRVAGAVH GGLHPDRGSF AEYLKVDADL
AWRVPSTVSD ADATTYGVSA ITAMLSLNLR HGLSWADEGQ QAPTGKEIFI YGGSTSAGLF
HVQLAKIAGY KVITTASSRS ADLVKSYGAD AIFDYNKPNV AKEIVKAHPA IAKAVDCFGE
GPSTEICTEV LRNSGGKVVI LLPNGKSKVP GVTLELIMAY TLMGKAFQWL PPVGPKFEAS
PTDRAGLARF YKSLPELTAT LKPVPVSVSE GGFTEILAGL DKLRQKKVAG SKLVVKF
//
