ID G2YD49_BOTF4 Unreviewed; 1239 AA.
AC G2YD49;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Similar to dynactin {ECO:0000313|EMBL:CCD49697.1};
GN ORFNames=BofuT4P153000022001 {ECO:0000313|EMBL:CCD49697.1};
OS Botryotinia fuckeliana (strain T4) (Noble rot fungus) (Botrytis cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=999810 {ECO:0000313|EMBL:CCD49697.1, ECO:0000313|Proteomes:UP000008177};
RN [1] {ECO:0000313|Proteomes:UP000008177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T4 {ECO:0000313|Proteomes:UP000008177};
RX PubMed=21876677; DOI=.1371/journal.pgen.1002230;
RA Amselem J., Cuomo C.A., van Kan J.A., Viaud M., Benito E.P., Couloux A.,
RA Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.M.,
RA Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA Grossetete S., Guldener U., Henrissat B., Howlett B.J., Kodira C.,
RA Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA Zeng Q., Rollins J.A., Lebrun M.H., Dickman M.;
RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT sclerotiorum and Botrytis cinerea.";
RL PLoS Genet. 7:E1002230-E1002230(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00011010}.
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DR EMBL; FQ790321; CCD49697.1; -; Genomic_DNA.
DR AlphaFoldDB; G2YD49; -.
DR STRING; 999810.G2YD49; -.
DR eggNOG; KOG0971; Eukaryota.
DR HOGENOM; CLU_002523_1_1_1; -.
DR InParanoid; G2YD49; -.
DR Proteomes; UP000008177; Unplaced contigs.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1170.10; -; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR022157; Dynactin.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12455; Dynactin; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000008177}.
FT DOMAIN 29..67
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 74..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1052..1103
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1138..1165
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 74..88
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1239 AA; 138296 MW; BA10BF5F1A758815 CRC64;
MAELEIGQTV ELGNGAIATI LWIGTDPIFA SGDWVGVELE DGGGKNDGSV LGRRYFQCEM
GKGMFVRPST IAIIDRPAPP PKAPAPAKKP GRPSSVVAPA ARRTNSVPDN GVKRKSMNAP
SPSPMGRQPS GPSGLRSPTK SPTKQLYSAG TSVTSTPKTG TPANSRAPSA GVTRPRPSSV
SRTSMGPPPP PGGRGKPLVG GSGLANRVGA PATRTAASRP TSLAPKRTLR PAPDRAPSGS
SQVSTGHLSD GTHEMVDEEG LLSPSLRSDT DQLSPQASSP IFTRTGREAS PAGSPAGQRI
ATSTAASREI EDLKTKLRVM EKKRMEDREK LKGLENVQAE KEKFEGIIQK LQTKYQPQQQ
ELTDLRKQLK EFAARFEEVE GMQAEHESIL EMATLDREMA EETAEVLRTE LDALKQKTEE
LELEVEVLRE ENTELGGEMS AEEKTSQSYL QLERKNERLT EALLRLRDLT QQAEAELKDE
IKSLQEDVRD LGSVKENYDA VKGKLAQSEA IIEDLRQQLD NALGAEDMIE ELTDRNMSMS
EQIEELKVTI EDLESLKELN DELEINHVET EKEMQEEIDF KESIINEQAR RAAQQDETLD
DMEYTLSRFR ELVTSLQSDL EDIRASHAVT ETESEQLNSR TRAMQDLNMK LQVSAAKTQV
KTIDLELRRL DAQEASEHLS IVQLFLPDQF NTERDSVLAL LRFRRVAFKA NLLHGFVKER
VNGQPPIGHE DDIFAGCDVL DKLVWVGAMC NRFFNAISHC SIEEFGKYEG ALYELEPVER
ALNGWIDGLR RDELKEKQCA SELQRTIALM SHLAEVHLGD SLANYADEVY MRTLVMQSQL
ENAAAAISSA RTMVQTIIPS QEEDDELFEH FSKKTEAVIT QTRSAKVIVG KAVREIEDMK
ARSLSLMPDT IESFEQCELA TQQLADYTRH VGNDLFTVLH EEGRAEPYTY VEVQSTIYQT
TSNILSTDES DLFSTYSNKL RLLNNQLINL STLTSDLDKT LEFELATAPW ILRSQELKSS
KTVTVDTQEE LRRLKEDNHE RLRLIALRDQ TLEESSVKIE LLESRMRDAT KKNERINELE
RKIEVAKNRE AELAEAIELQ NKELSTMEAD REKWKKIADE SKALGEVVSG SKAGQERAVA
TAREMDALKT EIASLQAAVR YLREDNRRVK LSERENMSWL DEPLIKSKSV EEQRKALVIA
EGQDVLSELL TLATGENSRI YDLGAIKADR GKWRPAKSC
//
