ID G2Z185_FLABF Unreviewed; 639 AA.
AC G2Z185;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=WbpM protein involved in UDP-D-Qui2NAc biosynthesis (A nucleotide sugar for antigen-O biosynthesis) {ECO:0000313|EMBL:CCB69648.1};
GN Name=wbpM {ECO:0000313|EMBL:CCB69648.1};
GN OrderedLocusNames=FBFL15_1584 {ECO:0000313|EMBL:CCB69648.1};
OS Flavobacterium branchiophilum (strain FL-15).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1034807 {ECO:0000313|EMBL:CCB69648.1, ECO:0000313|Proteomes:UP000009186};
RN [1] {ECO:0000313|EMBL:CCB69648.1, ECO:0000313|Proteomes:UP000009186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FL-15 {ECO:0000313|EMBL:CCB69648.1,
RC ECO:0000313|Proteomes:UP000009186};
RX PubMed=21926215; DOI=10.1128/AEM.05625-11;
RG 1:IP;
RG Microbial Evolutionary Genomics,F-75015 Paris;
RG France 2:CNRS;
RG URA2171;
RG F-75015 Paris,France 3:Unite de Virologie et Immunologie Mol.;
RG INRA,78352 Jouy en Josas Cedex;
RG France. 4:Unite de Mathemathique;
RG Informatique et Genome,INRA;
RG 78352 Jouy en Josas Cedex;
RG France. 5:CEA/Genoscope;
RG Evry;
RG France;
RA Touchon M., Barbier P., Bernardet J.F., Loux V., Vacherie B., Barbe V.,
RA Rocha E.P., Duchaud E.;
RT "Complete genome sequence of the fish pathogen Flavobacterium
RT branchiophilum.";
RL Appl. Environ. Microbiol. 77:7656-7662(2011).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; FQ859183; CCB69648.1; -; Genomic_DNA.
DR RefSeq; WP_014084115.1; NC_016001.1.
DR AlphaFoldDB; G2Z185; -.
DR STRING; 1034807.FBFL15_1584; -.
DR KEGG; fbr:FBFL15_1584; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_10; -.
DR Proteomes; UP000009186; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009186};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 301..589
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 639 AA; 73268 MW; 6003ACD1A0878A9A CRC64;
MKKNLKIQLR EKITNLNYLP RWIILIIDFT IIIACLFFTD FLLSKMNKAL YFHGYFVEAL
SLYFGTNLFC FYFFKSYSGI IRHSSIQDTF KIFKVQVVTL LTLLFINNAY FFNFVKYFGN
AGLVINFIFC FTLLVLFRVF VKLTFEYYFS TVSSRKDEIR VLVYGTDTNS ISVVNSIQTN
KTQKYKVVGF IDHRYGNTNK LLLALPIFSN KSRIPALLRV NNCQGIILTD ASLTIIEKTK
IVNDCLEFNF KVFTVPKISN LENGQEVSNR IKHFDINDLL ERDSIIINNH KIAEQHEATC
VLVTGAAGSI GSEIVRQMYK FSPKKIILLD QAESPLNDLT LEIEKIFTNQ IELLPLIGDV
RNYNYIDAIL KEHKPDIIYH AAAYKHVPLM EINPKQAIQT NIIGTKTVAT LAIKYQVKKF
VLVSTDKAVN PSSVMGASKR IAELTVQYLN QLSFMNKDFH TEFIITRFGN VLGSNGSVVP
LFTRQINEGG PVTLTHPDII RYFMTIPEAC QLVLEAGIMG SGGEIFIFDM GEPVRIYDLA
VKMIKLAGYQ PNKDIEIKVT GLRPGEKLYE ELLNDKAKTK ETYHKKIMIS IDHETNLEEI
YQQILQLIEN YLENNDEVVV SQMKEIVPEF ISLNSFYKN
//
