ID G2Z3E4_FLABF Unreviewed; 1883 AA.
AC G2Z3E4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Probable lipoprotein {ECO:0000313|EMBL:CCB68257.1};
GN OrderedLocusNames=FBFL15_0101 {ECO:0000313|EMBL:CCB68257.1};
OS Flavobacterium branchiophilum (strain FL-15).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1034807 {ECO:0000313|EMBL:CCB68257.1, ECO:0000313|Proteomes:UP000009186};
RN [1] {ECO:0000313|EMBL:CCB68257.1, ECO:0000313|Proteomes:UP000009186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FL-15 {ECO:0000313|EMBL:CCB68257.1,
RC ECO:0000313|Proteomes:UP000009186};
RX PubMed=21926215; DOI=10.1128/AEM.05625-11;
RG 1:IP;
RG Microbial Evolutionary Genomics,F-75015 Paris;
RG France 2:CNRS;
RG URA2171;
RG F-75015 Paris,France 3:Unite de Virologie et Immunologie Mol.;
RG INRA,78352 Jouy en Josas Cedex;
RG France. 4:Unite de Mathemathique;
RG Informatique et Genome,INRA;
RG 78352 Jouy en Josas Cedex;
RG France. 5:CEA/Genoscope;
RG Evry;
RG France;
RA Touchon M., Barbier P., Bernardet J.F., Loux V., Vacherie B., Barbe V.,
RA Rocha E.P., Duchaud E.;
RT "Complete genome sequence of the fish pathogen Flavobacterium
RT branchiophilum.";
RL Appl. Environ. Microbiol. 77:7656-7662(2011).
CC -!- SIMILARITY: Belongs to the protease inhibitor I39 (alpha-2-
CC macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
CC {ECO:0000256|ARBA:ARBA00010556}.
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DR EMBL; FQ859183; CCB68257.1; -; Genomic_DNA.
DR RefSeq; WP_014082737.1; NC_016001.1.
DR STRING; 1034807.FBFL15_0101; -.
DR KEGG; fbr:FBFL15_0101; -.
DR eggNOG; COG2373; Bacteria.
DR HOGENOM; CLU_000965_2_1_10; -.
DR Proteomes; UP000009186; Chromosome.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd02891; A2M_like; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.60.40.1930; -; 1.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR047565; Alpha-macroglob_thiol-ester_cl.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR021868; Alpha_2_Macroglob_MG3.
DR InterPro; IPR041203; Bact_A2M_MG5.
DR InterPro; IPR041462; Bact_A2M_MG6.
DR InterPro; IPR041246; Bact_MG10.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR40094; ALPHA-2-MACROGLOBULIN HOMOLOG; 1.
DR PANTHER; PTHR40094:SF1; UBIQUITIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF17973; bMG10; 1.
DR Pfam; PF11974; bMG3; 1.
DR Pfam; PF17972; bMG5; 1.
DR Pfam; PF17962; bMG6; 1.
DR Pfam; PF01835; MG2; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SMART; SM01419; Thiol-ester_cl; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000313|EMBL:CCB68257.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009186};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1883
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003441050"
FT DOMAIN 1021..1163
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
FT DOMAIN 1226..1317
FT /note="Alpha-2-macroglobulin"
FT /evidence="ECO:0000259|SMART:SM01360"
SQ SEQUENCE 1883 AA; 209920 MW; 7436057A822999F0 CRC64;
MNAKNLVTAC LTILFVMACS HKTPADFNSD LSKFKNFITS FSGGLVAAQS DIRVVLAFEN
PNWKTNQPLD NDLFDISPNI EGKVVALSPH IVAFVPNEKL ESGTTYQVTL HVSKIKAVPK
ECEDFNFTVQ TIKQDFIINT LDIQSYSPDK QYLNAVLKTA DVMSLETAKK IIHAQQDGEN
LPIKFEEDVK SGTAFKLIID QIKRSDDASE IEVEYDGTDF GIDQKGSFKY AISAKNDFKI
VAIDTPEDDV KMISINFSEP LQKSQDFSGL VSIEQAKNLK FSAQGNVLKV YFNGENKLEK
PIEPVNTIAM VSDTTAIVVD TVMAATDSVA TVIEADAPEN DTPEVNLSHL KIEVFQGIES
QYGTKMKENY NNSISLEPLK PDVRFIKNGT ILPSSNNLKI NFEAVNLSAV DVKVYKIYKN
NILQFLQENE LNGARNLKRV AQPIAKSKIE LNKNQLLQNT KWNAYSLDLS KIITPEPGAI
YRVEMSFNKK YSLYKCNDST TDTNTVEEEA IDEKDVNYSD SYDDYYYDDF EWRESQDPCS
DSYFYNARVG TNILASDLGV IAKRGENKSY HFTVANIVDT TPIENATVTL YSYQQQKLGS
QSTDSQGFAT FKLDTFAYFA IVTKGKQATY VKLDDGLSLS VSNFDVSGEV LQKGLKGYLY
GERGVWRPGD DLYLSFILND QANKLPLGHP IKFKLNDPNG KTTYETVQKT NELNHYSFII
PTNADAPTGS WEAVVSVGGA KFYKNIKIET IKPNRLKIKN IFQAPILSAA HQNTDNLEVA
WLHGAVAKNL KVVMEAKFSE QTTVFKHYEK YIFDDETRKF NTEETTIFSG TLDAAGKVSI
PIQPKIQGQA PGLLRAAMIT KVFEEGGDFS TDVVAMQYAP YHTYVGLKLP ELTPYQMLET
RKNNVFEVVT VDENGQPKAN RQLEVSIFKV QWRWWWDASE DNISNYNTSN ANTAFKTFSI
STDQSGKGRF QFSLKDEEWG RYLIRISDPS GGHATSSSVN IDWPSWSGKT RNTDATSANM
LVFSTNKKEY AVGETATIAF PSSAGGRALI AIENGSKVLK TIWAKTTAGE TKVSVPITAD
MAPNVYFNIT LLQPHAFTKN DSPIRMYGIV PIAVIDKNTI LQPQITMPEV LKPEQNFNLK
VSEKTGKSMT YTIALVDEGL LDLTRFKTPN AWDNFYAREA LGVKTWDIYD NVIGAYGGKI
NQIFSIGGDQ DLGGGKTKKA NRFKPVVIHL GPFSLGKGDS KTHQIKLPKY IGSVRAMLVA
ANAQQNAYGS TEKAVPVRSP LMALASVPRK ISPAERVTIP VTIFAMEKHV KNVSIQIKTN
NGIRVLGNTT QKLTFNQPDE KMVYFDLAVG QATGIGKIQV IATSGKERSV YDVSIDMTNP
NPITNLYTDV VVAPHTSQTI SWKTFGIYGS NAAKIEVSSM PNLNFNNRLQ YLIAYPHGCV
EQTTSSVFPQ LYLSDVCDLD ANRLAMIQKN VTAGINRLSG FQLPSGGLSY WQGQSNPDDW
GTSYAGHFLI EAEKKGYVLP LNFKQKWISF QQKTAKNWRF ESSFENDLAQ AYRLYTLALS
GNPDLASMNR LRETNNISNE AKLRLAAAYT LAGQKAAGNA LLLKSQIEPN ENPHQVYNYY
GSAERNAAMT LESLILLGQQ QKSFIMAQKL AKKMATNEWM STQTTAYCLY AMSKFTQVNG
GKGIQMAWTK NGKSDRIYTT KATANRDLEV TSGNNSMVVK NNHNNTVYVR VMQSGILPIG
QEQTAMNNLV AQVVFKNRKG EKLQMAKINQ GTELIAEVQI TNLQNEMVSN MALSQILPSG
FEIVNTRYTD FGEATHNVAD YIDIRDDRTH FYFALKSRET KTFKILLNAS YLGTYYLPGL
QCEAMYDHSV LARTKGFWVA IVK
//
