ID G3AEW1_SPAPN Unreviewed; 2024 AA.
AC G3AEW1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=RNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPAPADRAFT_131497 {ECO:0000313|EMBL:EGW35791.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW35791.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
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DR EMBL; GL996499; EGW35791.1; -; Genomic_DNA.
DR RefSeq; XP_007373203.1; XM_007373141.1.
DR STRING; 619300.G3AEW1; -.
DR GeneID; 18869581; -.
DR KEGG; spaa:SPAPADRAFT_131497; -.
DR eggNOG; KOG0951; Eukaryota.
DR HOGENOM; CLU_000335_1_0_1; -.
DR InParanoid; G3AEW1; -.
DR OMA; QTEIQYY; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProt.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041094; Brr2_helicase_PWI.
DR InterPro; IPR048863; BRR2_plug.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF21188; BRR2_plug; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF18149; Helicase_PWI; 1.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709}.
FT DOMAIN 401..582
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 592..823
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1242..1413
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2024 AA; 230441 MW; FF82200942444A38 CRC64;
MANKVIRQPR KGTSEQEVPA SSMAGRINAK DMGSNYKPEH KTVTKTTKQE ENSSLPNYQL
FEVFMTKIRT YLPDSSHEVI RSATELAVEY LSKPDLSVVK KREELEELLS AKVDDVDLNV
LINLTDKMNE LNSVKQDDNE NEYIAVDFDS SDEEQGQADV EVEVEEDEEQ PEGEQEVIEL
PEVSKDPEVV NIAWLEQEVL KASKTHELST SAELLLSDTI RLLSDVELTV NELDNSLNEV
FEYECSDLIV KCIENRWRIV FTKKLSEATS EETRQEIYQE MEALHLEQLA SELEDKKRSA
FDDEAEVTSV KRVKQGKRIP QRISLDKIQF STSVEGTKVI LPKGSFQQNK KSYDIITVPP
VEQAPQTEDL LPINSLPDWA RDAFPSNETT TFNRIQSKIF PQAFETDNNL LICAPTGAGK
TNVAMLTILR TISNFRTEAG RILLKQFKII YIAPLKALVQ EQMREFQRRL TSYGLVVNEL
TGDSTLSKRQ ILETQIIVTT PEKWDIITRK DPSYISLTRL IIIDEIHLLH DERGPALENI
VGRTLRKSET TGNQVRLVGL SATLPNYADV AKFIQVPEEG LFYFDASFRP CPLQQEFVGI
KERSAIKKLN AMNEACFDRT LNSLERGHQL IIFVHSRKET YTTAKYLMDK MASSEVNMVD
TLGVKEILKQ EGESMSNKHL KEIIPNGFGI HHAGLSRNDR NVVEDLFASG HLRVLVSTAT
LAWGVNLPAH TVIIKGTETY SPEIGTWVQL SPQDILQMLG RAGRPRYDKN GEGIIITSQD
EIQYYLAILN QQLPIESKLI SKLVDSVNSE VVSGSITTLE EGIEWLSYTY FFVRMLHSPA
LYGIEADYDF KGDPTLHNRR ADLIYTALAI LHENKLVMFE SETGLVKSTE LGKISSYYYI
NYETINLYGK MLKPWYNEID ILRVFSNSGE FKYVPVRQEE RLEVSKLMEK CPIPIKEQPH
EAVAKINILL QTYISRLALE GYALISDMIY ITQSAGRLLR AIYEISLLKK WSGLSKIVLD
LCKMVDKRIW LNNSPLRQFG SLVPDQIIRA TEMSHLPWNR YFQLTVEELA EAINLKGNAK
VASEFIQAFP RISIQYFVQP ISSKFLRVQI EAVPEWSWMS VHGSQEMFMV FLEDCNGNQL
LHHEEFVVKQ QNINKVHVVE FIVPVSEPLI PNFVVSFISN KWVNCNWKVP IMLTNVEVPS
LSSYYLDNSD VQLVSTKDLK KQEFIDLFPF TFFNKVQSAT FDVVYHTNEN VFIGSSKGDG
KTVCAELAIL NHWRQNKGRV VYINPSTEII DDNLKKWSNS FDVFEKSVNK LTGTLRQDIA
ILNESHLVLA TPEQFANLSK RWKTKKSFKS IDLLILDDIH FIGSLPTYEI LVSRIRMLTS
QWDNMLRIVA LASPVANCRD LCDWIGVGKS NVFNFPPQSR QNSISEIKLS PEGSVVPIVK
IYKELKRLNV GLRKSVIFVP TRVKALELAR QLLDYMAGSH DWRRVDLLKL EKYIEKVEDN
TLRELLGRGI AVYFENMSRV DKLIVEKLFE SNSIGILIAT KNTCKYAPHG HNLLVVGTQT
YDGYEHRNVD CNSNEIFEMV GCCQDDLANE GKVHIYTENK TIEFYGSLLN DGLIVESLLL
SSISEFFMGA ISNGVVRSKQ DCIDLLTFSY FYRRLVKNPG FYELKNATSL GVSEYLSELI
ENAIEELEKN EFVEIEQDEE EETILPLNKT IIASHYSISY ETMKLFGSLT SKSKLKDILL
IITSASEFES IPVREEDGNV LSRLGQKVPI KLNGEHDIES PLYKSFILLQ SHISRIEVPA
ELAQDRNTVV TKVLDILNAC IDCLSGEGHL NALLAMDLSQ MIIQAVWSTG AGSALRQIPY
FDDAILARCE KHNVETVYDI MSLEDEERDE VLQLEGDRLN SVANFVNQYP NIEISYEMDT
ATPCVANEPK EITIKIERDE EMESLQVVCD KYPSAREEGW WLVIGDAQLR QLYAIKRVSL
GLESQNFTLE FTVPTKGKAN LTVWSICDSY IDADKEINFD IEVV
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