ID G3AZH6_CANTC Unreviewed; 838 AA.
AC G3AZH6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
GN ORFNames=CANTEDRAFT_101864 {ECO:0000313|EMBL:EGV65580.1};
OS Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC
OS 10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Yamadazyma.
OX NCBI_TaxID=590646 {ECO:0000313|Proteomes:UP000000707};
RN [1] {ECO:0000313|EMBL:EGV65580.1, ECO:0000313|Proteomes:UP000000707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 /
RC NRRL Y-1498 / VKM Y-70 {ECO:0000313|Proteomes:UP000000707};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448,
CC ECO:0000256|RuleBase:RU361161};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|RuleBase:RU361161}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR EMBL; GL996512; EGV65580.1; -; Genomic_DNA.
DR RefSeq; XP_006684154.1; XM_006684091.1.
DR AlphaFoldDB; G3AZH6; -.
DR STRING; 590646.G3AZH6; -.
DR GeneID; 18245508; -.
DR KEGG; cten:CANTEDRAFT_101864; -.
DR eggNOG; ENOG502QR4D; Eukaryota.
DR HOGENOM; CLU_004542_4_0_1; -.
DR OrthoDB; 5486783at2759; -.
DR UniPathway; UPA00696; -.
DR Proteomes; UP000000707; Unassembled WGS sequence.
DR GO; GO:0008422; F:beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102483; F:scopolin beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF28; BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR Pfam; PF07691; PA14; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SMART; SM00758; PA14; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
DR PROSITE; PS51820; PA14; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361161};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Polysaccharide degradation {ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000000707}.
FT DOMAIN 398..560
FT /note="PA14"
FT /evidence="ECO:0000259|PROSITE:PS51820"
SQ SEQUENCE 838 AA; 93035 MW; 06CEF331B6BF7174 CRC64;
MADIDVEYTL SQLELSEKIG LIAGIDFWHT FAVKRLNIPS LRLSDGPNGT RGTRFFDGVP
AACFPCGTGL GSTFNKELLQ KAGQLMGVEA KHKGAHVILG PTTNMQRGPL GGRGFESFSE
DPYLAGIASA AIINGIQDED IAATIKHFVC NDLENERQSS DVIVTQRALR EIYLEPFRLA
IKYSNPACFM TAYNKVNGTH VSNNSKILKD ILRDEWKFEG LVMSDWFGVY TSEKAIQSGL
DLEMPGPTIF RSVEIIKHMI ESRELHIDDL DDRVRNVLNL VKWCAKSGVP ENGEEDTDND
TKETSALLRQ IAAESVVLLK NEDNVLPLKK DDKIAVIGPN AKYPAYSGGG SASLRPYYTT
TPFESISKKL STTPEYTVGA YAFKSMPSLA TQLTNFSTGK TGYNMKFYKH PRDYKGDREN
IDELNINTSF IFLVDYKNDK LDSNLYYIDI EGDFVPESSG EYEFGLTVQG TALLYVNDQL
VVDNKTKQEK GEAFFNMGST EITNKINLKG GEKYRVRVEF GSAPTFTASN GENVDFGGGG
GLFFGCAKVI DDDEEIANAV KLAKSVDKVV LAIGLNQEWE SEGYDRKDMD LPLRTNDLVE
AVLKANPNTV IVNQSGTPVE MPWLSKAKGL LQAWYGGNEG GNGIADVLFG DHNPSGKLSL
TFPFKNIDNP AYLNFKTERG RVLYGEDIFI GYRYYDKLQK KVAFPFGYGL SYTNFEYSDL
KINVDEAKDK LTASLSVKNV GKVDGAEVVQ LYISHKGGKT ILPVKELKGF EKVSIKAGKS
VTVSFDLCLK DTCSWFDEYF DKWILETGDY EVQIGKSSDD IELIAPFEIK NQKLWKGI
//
