ID   G3GHY2_9BACL            Unreviewed;       461 AA.
AC   G3GHY2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   08-NOV-2023, entry version 37.
DE   SubName: Full=Conjugative transposon FtsK/SpoIIIE family protein {ECO:0000313|EMBL:AEM62975.1};
OS   Bhargavaea cecembensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Bhargavaea.
OX   NCBI_TaxID=394098 {ECO:0000313|EMBL:AEM62975.1};
RN   [1] {ECO:0000313|EMBL:AEM62975.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DMV42A {ECO:0000313|EMBL:AEM62975.1};
RX   PubMed=23595824; DOI=10.1093/jac/dkt127;
RA   You Y., Hilpert M., Ward M.J.;
RT   "Identification of Tet45, a tetracycline efflux pump, from a poultry-
RT   litter-exposed soil isolate and persistence of tet(45) in the soil.";
RL   J. Antimicrob. Chemother. 68:1962-1969(2013).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JF915701; AEM62975.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3GHY2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR22683:SF47; FTSK DOMAIN-CONTAINING PROTEIN YDCQ; 1.
DR   PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50901; FTSK; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          211..392
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   BINDING         228..235
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ   SEQUENCE   461 AA;  53440 MW;  49F20D18017F6220 CRC64;
     MKQRGKRIRP SDKDLVFHFT IASLLPVFLL VVGLFHVKTI QQINWQDLDL LQVDKIDIPY
     LVISFSVAIL VCLLGAFIFR RYKYDMFKQL QHRQKLAKMI LENKWYESEQ VKTDGFFKDS
     TSRTKEKITY FPKMYYRLKD GLISIRVEIM LGKYQDQLLH LEKKLESGLY CELTDKELKD
     SYVEYTLLYD TIANRLSIDE VQAKDGKLRL MTNVWWEYDK LPHMLIAGGT GGGKTYFILT
     LIEALLHTNS KLTILDPKNA DLADLGSVMG NVYYRKDDML SCIDRFYDEM MKRSEVMKKM
     ENYKTGENYA YLGLPAHFLI FDEYVAFMEM LGTKENTAVL NKLKQIVMLG RQAGFFLILA
     CQRPDAKYLG DGIRDQFNFR VALGRMSEMG YGMMFGSDVQ KDFFLKQIKG RGYVDVGTSV
     ISEFYTPLVP KGHDFLEEIK RLSHSKQDTQ ATCEAEVAGV D
//