UniProt: G3GUG6

Database: UniProt
Entry: G3GUG6_CRIGR

LinkDB:  G3GUG6_CRIGR 
Original site:  G3GUG6_CRIGR

All links

Ontology (10)   
   GO (10)   
Gene (4)   
   KEGG GENES (1)   
   ENSEMBL-UP (3)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (11)   
   InterPro (6)   
   Pfam (3)   
   PROSITE (2)   
Literature (1)   
   PubMed (1)   
All databases (32)   

Download RDF

ID   G3GUG6_CRIGR            Unreviewed;       822 AA.
AC   G3GUG6;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Lysine demethylase 1B {ECO:0000313|Ensembl:ENSCGRP00001017505.1};
DE   SubName: Full=Lysine-specific histone demethylase 1B {ECO:0000313|EMBL:EGV95567.1, ECO:0000313|RefSeq:XP_027265790.1, ECO:0000313|RefSeq:XP_027265791.1};
GN   Name=Kdm1b {ECO:0000313|Ensembl:ENSCGRP00001017505.1,
GN   ECO:0000313|RefSeq:XP_027265790.1, ECO:0000313|RefSeq:XP_027265791.1,
GN   ECO:0000313|RefSeq:XP_027265792.1};
GN   ORFNames=I79_001325 {ECO:0000313|EMBL:EGV95567.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV95567.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
RN   [2] {ECO:0000313|EMBL:EGV95567.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSCGRP00001017505.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [4] {ECO:0000313|RefSeq:XP_027265790.1, ECO:0000313|RefSeq:XP_027265791.1}
RP   IDENTIFICATION.
RC   STRAIN=17A/GY {ECO:0000313|RefSeq:XP_027265790.1,
RC   ECO:0000313|RefSeq:XP_027265791.1};
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_027265790.1,
RC   ECO:0000313|RefSeq:XP_027265791.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH000030; EGV95567.1; -; Genomic_DNA.
DR   RefSeq; XP_003496061.1; XM_003496013.3.
DR   RefSeq; XP_007609194.1; XM_007611004.2.
DR   RefSeq; XP_027265790.1; XM_027409989.2.
DR   RefSeq; XP_027265791.1; XM_027409990.2.
DR   RefSeq; XP_027265792.1; XM_027409991.2.
DR   STRING; 10029.G3GUG6; -.
DR   PaxDb; 10029-XP_007609194-1; -.
DR   Ensembl; ENSCGRT00001021749.1; ENSCGRP00001017505.1; ENSCGRG00001017531.1.
DR   KEGG; cge:100767337; -.
DR   eggNOG; KOG0029; Eukaryota.
DR   GeneTree; ENSGT00940000157751; -.
DR   OMA; AVYYDMD; -.
DR   OrthoDB; 5402444at2759; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   Proteomes; UP000694386; Unplaced.
DR   Proteomes; UP001108280; Chromosome 3.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0000786; C:nucleosome; IEA:Ensembl.
DR   GO; GO:0071949; F:FAD binding; IEA:Ensembl.
DR   GO; GO:0140682; F:FAD-dependent H3K4me/H3K4me3 demethylase activity; IEA:Ensembl.
DR   GO; GO:0042393; F:histone binding; IEA:Ensembl.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0044726; P:epigenetic programing of female pronucleus; IEA:Ensembl.
DR   GO; GO:0071514; P:genomic imprinting; IEA:Ensembl.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.100; -; 1.
DR   Gene3D; 3.90.660.10; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR007526; SWIRM.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR011124; Znf_CW.
DR   PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR   PANTHER; PTHR10742:SF413; LYSINE-SPECIFIC HISTONE DEMETHYLASE 1B; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   Pfam; PF04433; SWIRM; 1.
DR   Pfam; PF07496; zf-CW; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50934; SWIRM; 1.
DR   PROSITE; PS51050; ZF_CW; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000313|EMBL:EGV95567.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW   Transferase {ECO:0000313|EMBL:EGV95567.1};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00454}.
FT   DOMAIN          133..193
FT                   /note="CW-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51050"
FT   DOMAIN          277..375
FT                   /note="SWIRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50934"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          235..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..254
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   822 AA;  92268 MW;  5DB09011823E3D32 CRC64;
     MATPRGRARK RGSLELSADS LPLRSSGRQA KKKAVEITDE DEDGSLEKKY RKCEKAGCTA
     MYPVCFASAS ERCAKNGYTS RWYHLSCGEH FCNECFDHYY RSHKDGYDKY SAWKRVWTSN
     GKTEPSVKAF MADQQLPYWV QCTKPECGKW RQLTKEIQLT PHMARTYRCG IKLNTITKTD
     IPDHCSLPED LRVLEVSNQW WNSMLIQPPL LKDSVAAPLL SAYYPDCVGM SPSCTSTNRA
     TGTTTSSASP GKMEPSKVAS SPLVLGMNRY FQPFYQPNEC GKALCVRPDV MELDELYEFP
     EYSRDPTMYL ALRNLILALW YTNCKEALTL QKCIPQIIVR GLVRIRCIQE VERILYFMTR
     KGLINTGVLT VGAGQHLLPK QYHNKSVLVV GAGPAGLAAA RQLHNFGMKV TVLEAKDRIG
     GRVWDDKSFK GVVVGRGAQI VNGCINNPVA LMCEQLGISM HKLGERCDLI QEGGRITDPT
     IDKRMDFHFN ALLDVVSEWR KDKTLLQDVP LGEKIEEIYQ VFVKESGLQF SELEGKVLQF
     HLSNLEYACG SSLQQVSARS WDHNEFFAQF AGDHTLLTPG YSTIIEKLAE GLDIRLKSPV
     QSIDYTGDEV QVTTTDGMGH SAQKVLVTVP LAILQKGAIQ FNPPLSEKKM KAINSLGAGI
     IEKIALQFPY RFWDGKVQGA DFFGHVPPSA SQRGLFGIYY DMDPQQSVLM SVITGEAVAS
     LRTMDDKQVL QQCMSVLREL FKEQEIPDPT KYFVTRWSTE PWIQMAYSFV KTFGSGEAYD
     IIAEEIQRTI FFAGEATNRH FPQTVTGAYL SGVREASKIA AF
//

DBGET integrated database retrieval system