ID G3GWY9_CRIGR Unreviewed; 1048 AA.
AC G3GWY9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Putative methyltransferase TARBP1 {ECO:0000313|EMBL:EGW03333.1};
GN ORFNames=I79_002276 {ECO:0000313|EMBL:EGW03333.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW03333.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH000057; EGW03333.1; -; Genomic_DNA.
DR AlphaFoldDB; G3GWY9; -.
DR STRING; 10029.G3GWY9; -.
DR PaxDb; 10029-XP_007612536-1; -.
DR eggNOG; KOG0839; Eukaryota.
DR InParanoid; G3GWY9; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0016423; F:tRNA (guanine) methyltransferase activity; IEA:InterPro.
DR GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR CDD; cd18091; SpoU-like_TRM3-like; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR045330; Trm3/TARBP1.
DR InterPro; IPR044748; Trm3/TARBP1_C.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR12029:SF11; METHYLTRANSFERASE TARBP1-RELATED; 1.
DR PANTHER; PTHR12029; RNA METHYLTRANSFERASE; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:EGW03333.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transferase {ECO:0000313|EMBL:EGW03333.1}.
FT DOMAIN 891..1032
FT /note="tRNA/rRNA methyltransferase SpoU type"
FT /evidence="ECO:0000259|Pfam:PF00588"
SQ SEQUENCE 1048 AA; 118734 MW; CCA1A46B5DF8AB2A CRC64;
MLWTELCDWL RVNERYFRQS SIGGSDGQET SLNAYVKKLV QEFVKSPGWE RESCFMPDWL
EARLTSLMVL LAVDVEGMKT QFREKQRTQN VLRIFLDPLL DALGKLATNA YMPLLRTDRC
LQLLARLLHS CVPRGSSGQD DEVSSVLQTS IMSVADSVSQ FVLRRLTMNE LQSVADLDRC
QLYLKVLAEL TSLQVKQGWK AGNPISRVIS PLKNACIHHL QEAEDGEEPT LGHQVQRAVS
MATLAALCEA VDQHPVLQLD AEPMDRFLST LPLNQMLQKP RSEEQNGCVH PLENGSVFEE
SSSSQGWGKI AAQYLHDQWV CLSFLLRKHY PLIPTTESDR LECFLPAVEM PVQTLRSALD
VLTVLPAGCI LPVFRCMEVL VPKLLTSDES LCIESFDMAW KIISSLSNTQ LTFWPNLKAF
IHFVFNNEIL TIAAKLKGQG YFKIKEIMCK IIEMSSIKTG VFNILICHCC QSWIAAACGV
SHSSLFSSAK DYSELVLEAC VFGTVFRRDQ RLIQDVQTFI ENLGQDCAAN IIIENTKRED
YYVRICAVKF LCLLDGSDIS HKLFIEDLAI QLLDKDESTS RSRTRYHENS LQHRVKNRAW
QTLLVLFPRF DQNFLNGIID KIFHAGFTNN QASIKYFIEW IIILILHKFP QFLPKFWDCF
SYGEEKLKTS ICTFLSVLSH LDIIIQNIPE KRLVLKQALT IALQWCLSHN FSVRLYALVA
LKKAWQLCKA LKFEECDAWT TVIECSLSQA ESMHGAGNAR KNWQRIQDHF FFSTFHPLKD
YCLETIFYTL PRLSGITEEE WITLDKFASF TDIPSNTGSH WYLSGTALGE LSPGDWSQQD
RGYTLGEAES QSEWADVQKK IIPWGHKALE SDLELMFQDR AAKLGKSISR LIVVASLIDK
PTNLGGLCRT CEVFGAAVLV VGSLQCVSDR QFQHLSVSAE QWLPLVEVRP AQLTDYLQQK
KAEGYTVIGV EQTAQSSDLA QYRFPEKSLL LLGNEREGIP ANLIQQLDVC VEIPQQGIIR
SLNVHVSGAL LIWEYTRQQL LGCAGLAS
//
