ID   G3H0Q4_CRIGR            Unreviewed;       300 AA.
AC   G3H0Q4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=TOX high mobility group box family member 3 {ECO:0000313|EMBL:EGV92001.1};
GN   ORFNames=I79_003718 {ECO:0000313|EMBL:EGV92001.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV92001.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH000097; EGV92001.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3H0Q4; -.
DR   STRING; 10029.G3H0Q4; -.
DR   PaxDb; 10029-XP_007607811-1; -.
DR   eggNOG; KOG0381; Eukaryota.
DR   InParanoid; G3H0Q4; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd21995; HMG-box_TOX-like; 1.
DR   Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   PANTHER; PTHR45781; AGAP000281-PA; 1.
DR   PANTHER; PTHR45781:SF3; TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   PRINTS; PR00886; HIGHMOBLTY12.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; HMG-box; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          175..243
FT                   /note="HMG box"
FT                   /evidence="ECO:0000259|PROSITE:PS50118"
FT   DNA_BIND        175..243
FT                   /note="HMG box"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT   REGION          109..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          257..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..160
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   300 AA;  32569 MW;  910CE4121DB53179 CRC64;
     MPDVLLPFQA LSDPLPSQGN EFTPQFPPQS LDLPSITISR NLVEQDGVLH SNGLHMDQSH
     TQVSQYRQDP SLIMRSIVHM TDAARSGIMP PAQLTTINQS QLSAQLGLNL GGASVPHTSP
     SPPASKSATP SPSSSINEED TDEANRAIGE KRTAPDSGKK PKTPKKKKKK DPNEPQKPVS
     AYALFFRDTQ AAIKGQNPNA TFGEVSKIVA SMWDSLGEEQ KQVYKRKTEA AKKEYLKALA
     AYRASLVSKI TSPIPAIGSP QPASQQLQPQ IQSQTQTQVL PQAKPTICES NRLMNPGTYR
//