ID G3H8G6_CRIGR Unreviewed; 354 AA.
AC G3H8G6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Kelch domain-containing protein 8B {ECO:0000256|ARBA:ARBA00041086};
GN Name=Klhdc8b {ECO:0000313|Ensembl:ENSCGRP00001014867.1,
GN ECO:0000313|RefSeq:XP_027270367.1, ECO:0000313|RefSeq:XP_035299856.1};
GN ORFNames=I79_006666 {ECO:0000313|EMBL:EGW08948.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW08948.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW08948.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001014867.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:XP_027270367.1, ECO:0000313|RefSeq:XP_035299856.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_027270367.1,
RC ECO:0000313|RefSeq:XP_035299856.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_027270367.1,
RC ECO:0000313|RefSeq:XP_035299856.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Midbody {ECO:0000256|ARBA:ARBA00004214}.
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DR EMBL; JH000209; EGW08948.1; -; Genomic_DNA.
DR RefSeq; XP_007632986.1; XM_007634796.1.
DR RefSeq; XP_007639332.1; XM_007641142.2.
DR RefSeq; XP_007639333.1; XM_007641143.1.
DR RefSeq; XP_016827968.1; XM_016972479.1.
DR RefSeq; XP_027270367.1; XM_027414566.2.
DR RefSeq; XP_035299856.1; XM_035443965.1.
DR STRING; 10029.G3H8G6; -.
DR PaxDb; 10029-XP_007632985-1; -.
DR Ensembl; ENSCGRT00001019105.1; ENSCGRP00001014867.1; ENSCGRG00001015630.1.
DR KEGG; cge:100764543; -.
DR eggNOG; KOG1072; Eukaryota.
DR GeneTree; ENSGT00940000160815; -.
DR OMA; VWIKPSR; -.
DR OrthoDB; 884885at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR Proteomes; UP001108280; Chromosome 4.
DR GO; GO:0110070; C:cellularization cleavage furrow; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0045171; C:intercellular bridge; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR GO; GO:1902410; P:mitotic cytokinetic process; IEA:Ensembl.
DR GO; GO:0140014; P:mitotic nuclear division; IEA:Ensembl.
DR GO; GO:0098813; P:nuclear chromosome segregation; IEA:Ensembl.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR46260:SF2; KELCH DOMAIN-CONTAINING PROTEIN 8B; 1.
DR PANTHER; PTHR46260; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 354 AA; 37609 MW; 0B583CA13BE86F6D CRC64;
MAAGGGRAFA WQVFPPMPTC RVYGTVAHQD GHLLVLGGCG RAGLPLDTAE TLDMSSHTWL
ALAPLPTARA GAAAVVLGKQ VLVVGGVDEA QSPVAAVEAF LADEGRWERR ATLPQAAMGV
ATVERDGMVY ALGGMGPDTA PQAQVRVYEP RRDCWLSLPS MPTPCYGAST FLHGNKIYVL
GGRQGKLPVT AFEAFDLETR TWTRHPSLPS RRAFAGCAMA EGSVFSLGGL QQPGPHNFYS
RPHFVNTVEM FDLEHGSWTK LPRSLRMRDK RADFVVGSLG GNIVAIGGLG NQPCPLASVE
SFSLARRRWE ALPAMPTARC SCSSLQAGPR LFVIGGVAQG PSQAVEALCL RDGV
//
