ID   G3HI54_CRIGR            Unreviewed;       759 AA.
AC   G3HI54;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=E3 ubiquitin-protein ligase RNF10 {ECO:0000256|ARBA:ARBA00035131};
DE   AltName: Full=RING finger protein 10 {ECO:0000256|ARBA:ARBA00035390};
DE   Flags: Fragment;
GN   ORFNames=I79_010321 {ECO:0000313|EMBL:EGW10590.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW10590.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   -!- SIMILARITY: Belongs to the RNF10 family.
CC       {ECO:0000256|ARBA:ARBA00008117}.
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DR   EMBL; JH000399; EGW10590.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3HI54; -.
DR   STRING; 10029.G3HI54; -.
DR   PaxDb; 10029-XP_007607213-1; -.
DR   eggNOG; KOG2164; Eukaryota.
DR   InParanoid; G3HI54; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16536; RING-HC_RNF10; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR039739; MAG2/RNF10.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR12983; RING FINGER 10 FAMILY MEMBER; 1.
DR   PANTHER; PTHR12983:SF9; RING FINGER PROTEIN 10; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          174..215
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          1..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          671..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          724..759
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..65
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EGW10590.1"
SQ   SEQUENCE   759 AA;  84665 MW;  6A73A916438C7976 CRC64;
     SDGKNSNGSK RYNRKREPSY PKNENFSNQS RRSNSQKSKT FNKMPPQRGG GSSKPFSSSS
     NGGRRDEVAE AQRAEFSPAQ FSGPKKINLN HLLNFTFEPR GQAGHFEGSG HGSWGKRNKW
     GHKPFNKELF LQANCQFVVS EDQDYAAHFA DPDTLVNWDF VEQVRICSHE VPSCPICLYP
     PTAAKITRCG HIFCWACILH YLSLSEKAWS KCPICYSSVH KKDLKSVVAT ESRQYVVGDT
     ITMQLMKREK GVLVALPKSK WMNVDHPIHL GDEQHSQYSK LLLASKEQVL HRVVLEEKVA
     LEQQLAEEKH TPESCFIEAA IQEVKIREEA LSGVAGGRGE VTGVVTALEQ LVLMAPLVKE
     SVFQPRKGVL EYLSAFEEET AEVCSLDSPR SLALPLVEEE EAVSEPEPEG LPEACEESEV
     ADDNLGEGTI CTESSQEEPI TKPGFTQLSS SPCYYFYQAE DGQHMFLHPV NVRCLVREYG
     SLEQSPEKIS ATVVEIAGYS MSEDVRQRHR YLSHLPLTCE FSICELALQP PVVSKETLEM
     FSDDIEKRKR QRQKKAREER RRERRIEMEE NKRQGRYPEV HIPLENLQQF PAFNSYTCSS
     GSAVGPTSTE GHGALSLSPL SRSPSSHADF LLTPLSPTAS QGSPSFCVGS LEEDSPFLSF
     AQMLRVGKAK ADVWPKTAPK KDENSLVPPA PVDSDGESDN SDRVPVPSFQ NSFSQAIEAA
     FMKLDTPATS DALSEDRGGK KRKKQKQKLL FSTSVVHTK
//