ID G3HIY2_CRIGR Unreviewed; 246 AA.
AC G3HIY2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=V-type proton ATPase subunit S1-like protein {ECO:0000313|EMBL:EGW09306.1};
GN ORFNames=I79_010615 {ECO:0000313|EMBL:EGW09306.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW09306.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC {ECO:0000256|ARBA:ARBA00009037}.
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DR EMBL; JH000415; EGW09306.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HIY2; -.
DR STRING; 10029.G3HIY2; -.
DR PaxDb; 10029-XP_007634344-1; -.
DR eggNOG; KOG3868; Eukaryota.
DR InParanoid; G3HIY2; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.160.110; -; 1.
DR InterPro; IPR008388; Ac45_acc_su.
DR InterPro; IPR046756; VAS1/VOA1_TM.
DR InterPro; IPR046755; VAS1_LD.
DR PANTHER; PTHR12471:SF3; V-TYPE PROTON ATPASE SUBUNIT S1-LIKE PROTEIN; 1.
DR PANTHER; PTHR12471; VACUOLAR ATP SYNTHASE SUBUNIT S1; 1.
DR Pfam; PF20520; Ac45-VOA1_TM; 1.
DR Pfam; PF05827; VAS1_LD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 171..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..150
FT /note="V-type proton ATPase subunit S1 luminal"
FT /evidence="ECO:0000259|Pfam:PF05827"
FT DOMAIN 166..201
FT /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF20520"
SQ SEQUENCE 246 AA; 28065 MW; E356D1E5F87C9413 CRC64;
MNMDEQDIKY FGYMLKTGIA RTYGISVFIF LRKLRADFHS GCTSFLSQLL SLRFGDAENP
KDIDIRLTLT NYNKLSSQSW FSLHRVEIIF NNSVQASFNA TGIYALSSYS YRCQRVSSLR
RNDALMLLSS SDDVTSLWEV TFIDFQIQGF SIKGAQFAQA RDCGSAFSPA VLIGLAMSLI
LLLVLAYALH MLIYLRYLDR HYEFITSPAH FPPLRELDTG EEKELLGSQG AECYELRSQQ
ICKIYI
//
