ID G3HSF6_CRIGR Unreviewed; 1185 AA.
AC G3HSF6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=AT-rich interactive domain-containing protein 4B {ECO:0000313|EMBL:EGV95692.1};
GN ORFNames=I79_013787 {ECO:0000313|EMBL:EGV95692.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV95692.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000661; EGV95692.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HSF6; -.
DR STRING; 10029.G3HSF6; -.
DR PaxDb; 10029-XP_007630825-1; -.
DR eggNOG; KOG2744; Eukaryota.
DR eggNOG; KOG3001; Eukaryota.
DR InParanoid; G3HSF6; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd16883; ARID_ARID4B; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR InterPro; IPR012603; ARID4A/B_PWWP.
DR InterPro; IPR028853; ARID4B_ARID/BRIGHT.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR025995; Tudor-knot.
DR PANTHER; PTHR13964:SF24; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4B; 1.
DR PANTHER; PTHR13964; RBP-RELATED; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF08169; RBB1NT; 1.
DR Pfam; PF11717; Tudor-knot; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS51011; ARID; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 178..270
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT REGION 16..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 138..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 783..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..178
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..339
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..439
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 518..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..661
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..723
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 735..759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..800
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..880
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..980
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1017..1061
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1083
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1185 AA; 133387 MW; CEC07F76BC0C1099 CRC64;
MGVQLRQFLS QFYTEHKNDV IPEEESSSSS SDDDEDDRKQ TDELLGKVVC VDYVSLDKKK
TLWFPALVVC PDCSDEIAVK KDNILVRSFK DGKFTSVPRK DVHEITSDSA PKPDAVLKQA
FDQALEFHKS RTIPANWKTE LKEDSSSSEA EEEEEEEDDE KEKEDNSSEE EEEIEPFPEE
RENFLQQLYK FMEDRGTPIN KRPVLGYRNL NLFKLFRLVH KLGGFDNIES GAVWKQVYQD
LGIPVLNSAA GYNVKCAYKK YLYGFEEYCR SANIDFQMAL PEKVLNKPCK DCENKEMKVK
EENETEIKEV NVEDNKNVTV KEETPAEDES ERKENIKPSL GSKKSLLESI PAQSDQEKEA
NIKKLEEKES SEDKDSDTAR AEESLSPEVD AEEEQARSGD ETNKEEDEDD EEIEEEEEEE
EEEEDEDEDD DDNNEEEEFE CYPPGMKVQV RYGRGKNQKM YEASIKDSDV EGGEVLYLVH
YCGWNVRYDE WIKADKIVRP ADKNVPKIKH RKKIKNKLDK EKDKDEKYSP KNCKLRRLSK
PPFQSNPSPE MVSKLDLADA KNSDTAHIKS IEITSILNGL QASESSAEES EQEDERGAQD
VDNSGRDESK VDHLTHTRNE LISKEEQSSP SLLEENKVHT DLVIAKTKSP ERLRKDVEGL
SEDTDFEEDD EITKKRKDVK KDTTDKSLKP QTKRGKRRYC NTEECLQTGS PGKKEDRTKS
KELLCTENSS NSSSDEDEEE KSKAKMTPTK KYNGLEEKRK SLRTTSFYSG FSEVAEKRIK
LLNNSDERLQ NSRAKDRKDV WSSIQGQWPK KTLKELFSDS DTEAAASPPH PAPDEGAVEE
SLQTVTEEES CSPIVELEKP LPASVDNKSV EEKPLEVSDR KTEFPSSGSN SVLNTPPTTP
ESPSSVTVTE ASQQQSSVTV SEPLAPNQEE VRSIKSETDS TIEVDSVVGE LQDLQSEGNS
SPAGFDASVS SSSSNQPEPE HPEKACTGQK RVKDAQGGGS SSKKQKRSHK ATVVNNKKKG
KGTNSSDSEE LSAGESVTKT QAVKSVPTGM KSHNSKSPAR MQSPGKCGKN GDKDPDLKEP
SNRLPKVYKW SFQMSDLENM TSAERISVLQ EKLQEIRKHY LSLKSEVASI DRRRKRLKKK
ERESAATSSS SSSPSSSSIT AAVMLTLAEP SMSSASQNGM SVECR
//
