ID   G3HZM5_CRIGR            Unreviewed;      1059 AA.
AC   G3HZM5;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Protein FAM65A {ECO:0000313|EMBL:EGV97047.1};
GN   ORFNames=I79_016532 {ECO:0000313|EMBL:EGV97047.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV97047.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   -!- SIMILARITY: Belongs to the RIPOR family.
CC       {ECO:0000256|ARBA:ARBA00005744}.
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DR   EMBL; JH000973; EGV97047.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3HZM5; -.
DR   STRING; 10029.G3HZM5; -.
DR   PaxDb; 10029-XP_007610036-1; -.
DR   eggNOG; ENOG502QQ7T; Eukaryota.
DR   InParanoid; G3HZM5; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR031780; FAM65_N.
DR   InterPro; IPR026136; RIPOR3.
DR   PANTHER; PTHR15829; PROTEIN KINASE PKN/PRK1, EFFECTOR; 1.
DR   PANTHER; PTHR15829:SF1; RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1; 1.
DR   Pfam; PF15903; PL48; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          1..207
FT                   /note="FAM65 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15903"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          213..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          337..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          450..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          552..629
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          695..722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..245
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        345..363
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        552..614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1059 AA;  113773 MW;  FED03FCD48B944D7 CRC64;
     MVRAYSTGSP GSREARDSLA EATRGHREYT ESMCLLENEL EAQLGEFHLR MKGLAGFARL
     CVGDQYEICM KYGRQRWKLR GRIESSGKQV WDSEETVFLP LLTEFLSIKV TELKGLANHV
     VVGSVSCETK DLFAALPQVV AVDINDLGTI KLSLEVIWSP FDKDDQPSAA STVNKASTVT
     KRFSTYSQSP PDTPSLREQA FYNMLRRQEE LENGTAWSLS SESSDDSSSP QLSGTARHSS
     TPKPLVQQPE PLPIQVAFRR PETLTSGSMD EEPAVSPALV NGHAPYSRTL SHISEASVDA
     ALTEAVEVVG SESLTPGPSP LAYPDSIHVE HLSSVPPILD AGHSATRPTP STTGPSPTLI
     DPASSTQLDL VHKATDSNPS ELPSLKHTSS TYSAVSPINS VPNITSTTID SIHKPMPSTL
     TTTGSIPNAA DPVQATPSPT HTTITLTHTT VSPTHSTPSP THTSVSPTCT VPSATNATPS
     PSYNTTSPIQ KTGMSTHATT SHTTNAMDPV LTTTSPISTT ESPNSAIDLA LTSSSSADLT
     LPGTKPLPCS HSASTPYTKT DPTASCTSSQ SLACSGSETL TSPAPNSPEQ ILKSPRFSPS
     SIAPAPQHSE LSPATAAQAP VPEATGGAGD KRLEEALGTL MAALDDYRGQ FPELQGLEQE
     VTRLESLLMQ RQGLTRSRAS SLSITVEHAL ESFSFLNDDE DEDSGARPTS SPEAVAEDRL
     DSSNAQSLST GCPALDATLV QHLYHCSRLL LKLGTFGPLR CQEAWALERL LREARVLEEV
     CERSKLWGNS ASSAQEVVQF SASRSGFLTF WDQCTEGLNP FICPVEQVLL TFCSQYGARL
     SLRQPGLAEA VCLKFLEDAL GRKLPRRPQP GPGEQFTIFQ FWIYVEALDS PSMDAYVTET
     AEEVLLVQNL NSDDQAVVLK ALRLAPEGRL RRDGLRALSS LLVHGNNKVM AAVSTQLRSL
     SLGPVFRERA LLCFLDQLED EDVQTRVAGC LALGCIKAPE GIEPLVYLCQ TDTEAVREAA
     RQSLQQCGEE GQSAHRRLEE SLDALPRIFG PSSMASTAF
//