ID   G3IDF0_CRIGR            Unreviewed;       929 AA.
AC   G3IDF0;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=Dynein heavy chain domain-containing protein 1 {ECO:0000313|EMBL:EGW13690.1};
GN   ORFNames=I79_021728 {ECO:0000313|EMBL:EGW13690.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW13690.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
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DR   EMBL; JH002047; EGW13690.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3IDF0; -.
DR   STRING; 10029.G3IDF0; -.
DR   PaxDb; 10029-XP_007612349-1; -.
DR   eggNOG; KOG3595; Eukaryota.
DR   InParanoid; G3IDF0; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR   GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.20.1270.280; -; 1.
DR   Gene3D; 3.10.490.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR041228; Dynein_C.
DR   InterPro; IPR043160; Dynein_C_barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10676:SF359; DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR   Pfam; PF18199; Dynein_C; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          608..923
FT                   /note="Dynein heavy chain C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18199"
FT   REGION          781..804
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          847..874
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        783..797
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        847..870
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   929 AA;  103198 MW;  42D0CB6B06F6332A CRC64;
     MQERLLVTLL LQNQKRQKPS KFLRAMVRTQ AKICQLNAQK EEIEEQKLED MILWAPYRQI
     ACHGMAIVEA LSPLQNLLPF FCMKLENWMA ATRQALDSMK PHDSYHGEDL ASHLLQLKIN
     LTRQLLTSTV AALGLTQAPL VGALGALALL QVTKKTPKLE RLAFWPGLSA SPSIGHNTQV
     PGVVRPAWLG LRAWQECGML ELLPPFAGLR ASLAGHSSVW QDYLSLSSTV LGPSPGPNSE
     PLSLLQKLIL WRVLRPDCLE GTLADLTTSL LGRPLDENLS NPTMIFEQNW ATQPILILLP
     PPGHPTAILH PLTVIRKLAA NHEKAMLQGH WLVLDNCHLM SHWPRELLQP LLRLLDGARV
     VSDSELLVEP ESSNVATVHR DFRLWLIVST EASSSLPGVL TWLSMPVFWD QSLELGRILI
     DSVGSQQGLC MQPLTQTLPL LLLHGLLLHR QLYGIKLQAH RGRWSQVTLT KVLQIQKHLW
     ASLSNPSAAL LELAASVFYG ASLKDPGDRE ALISLTGACL NPSNTSWVRY TPQYLLATLM
     PSPELGELDA MTECKARMHL LPTPAEPRAC GLNEGPKSWR LRRQSRALLN MLQQCSSTWV
     PSASGRNAQH KERRLRQRLV QAKKRLVALQ DLLTNGSCSG QSAIPWAVLG PNARRPLEGF
     LETEVLELRQ LVGILQRDLD CLLQQLKGKT PCTSSRCVAV AHALWAGRLP RPWRSHAPAG
     PQLPWHWLRH LSRRGNLLIR YLDSGTSENA NEPERIFHLS AFRHPRRLLL ALRWEAILES
     SEPCPNPTGT QGSGSGRVPP KRQELNNHPL HIRVENGPNP KVPKMGLLLI GLQLQHAEWD
     KMDGALQDSF SSQPSPLPPV SVSTQARGAS DARDSGGLDV YSCPVYMTGP LGTTKLHSKN
     ILMHLPLPTR LSPDTCIQRR VHVSSPTLS
//