ID G3J9H1_CORMM Unreviewed; 1019 AA.
AC G3J9H1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=ATP dependent DNA ligase domain protein {ECO:0000313|EMBL:EGX94948.1};
GN ORFNames=CCM_03220 {ECO:0000313|EMBL:EGX94948.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX94948.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX94948.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX94948.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
CC -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC {ECO:0000256|ARBA:ARBA00007572}.
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DR EMBL; JH126400; EGX94948.1; -; Genomic_DNA.
DR RefSeq; XP_006668434.1; XM_006668371.1.
DR AlphaFoldDB; G3J9H1; -.
DR STRING; 983644.G3J9H1; -.
DR GeneID; 18165246; -.
DR KEGG; cmt:CCM_03220; -.
DR VEuPathDB; FungiDB:CCM_03220; -.
DR eggNOG; KOG0966; Eukaryota.
DR HOGENOM; CLU_004299_4_0_1; -.
DR InParanoid; G3J9H1; -.
DR OMA; RIDEFWR; -.
DR OrthoDB; 2788069at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd08039; Adenylation_DNA_ligase_Fungal; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR029710; LIG4.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45997:SF2; ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430); 1.
DR PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:EGX94948.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610}.
FT DOMAIN 388..548
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
FT REGION 686..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..862
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1019 AA; 113098 MW; DE93E40D73DFC47B CRC64;
MPLPFSAVCD LLEQSSQLCQ QRKSNAAAVL AWFRRHRAAV DAHDADLAAL LSTLLPEKRT
DRVYCLQVPT LERIVGRALM LGASRMLELA TYKRPGAGVD FADCVERILS VTPNPIQESG
HQVTVEQVDE LLHSLAARIR WSAPAIRQSS ACMSHQSRGD LDAMYRRLSA RDAKWFTRLV
LKDYQPLFFD AHLLYRACDP VLPCLLQIRD DFTEALGAIP IARGALLPIA APRDSRPLCA
RRVLAAVKPK LGVKVGRQQW HKGRSIKHCM SMGSGRMSVE TKLDGEYCQI HVDMSKPKKR
VQIFSKSGKD STEDREKVIP AIERALRLNT TECVFKKACI LEGELLVYND LEKTIMPFHK
IRGHVTRRGR YFNTEQDSQP KPYEHLMIVY YDIFLLDDQG LMDVQHSERL KLLEKVIHYE
RGVAELVPRE TIDFGHSLAA STLRKAFAKV VVERGEGLVL KPDEPYIVIG PNGRTAPCRC
IKMKKEYIGA FGDVGDFALV GAGFHAAKAK TYRIPNLKWT HFYVGCLNNK EQVKRWGHKP
DFTVVCAVEL SEALLQSFLA LGELSAVSRA ANVATTLTVP PGIQCPANLT VAFTNPMVVD
LRCFSFDKPG NTGGLWTPRF PAVTKIHADR DYADVLTLDE LQALAKEAVE KPVLEDSQEN
LHWIARLEGA DPRGVAVDAV SQATATTMPT PSPANMTPST ASDSQSSKGA TEPSRRSQSL
ASAPVVNEVK GWRDASVSII SIPTTSTAEA VSPTKAAMQA PAKRVPEMAS PEQSLKRPRT
ASFRNTSPRK PLGNIDVNVS YSDSQSTNSQ DSQATVKRGP PRAQTVQRDV IEIPSSDAED
DDLQQPPSQE RHPQAVSHPP ASSQEEKDSK DQHWSCKHVG EKCGFVGKTM LLASPALLRV
AELTTLFGDH GVDVQRVLPC VETWWRSAGL RTAGAAVPQQ QKGCVVLLVD SVQQATETKA
LVARLNAARR QARREERDWI TVYDWRVLRH LSIAEDASVT KKYYDGFQDP WRRWYCGLV
//
