ID G3JC12_CORMM Unreviewed; 736 AA.
AC G3JC12;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Acetate-CoA ligase {ECO:0000313|EMBL:EGX93730.1};
GN ORFNames=CCM_01999 {ECO:0000313|EMBL:EGX93730.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX93730.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX93730.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX93730.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; JH126400; EGX93730.1; -; Genomic_DNA.
DR RefSeq; XP_006667216.1; XM_006667153.1.
DR AlphaFoldDB; G3JC12; -.
DR STRING; 983644.G3JC12; -.
DR GeneID; 18164028; -.
DR KEGG; cmt:CCM_01999; -.
DR VEuPathDB; FungiDB:CCM_01999; -.
DR eggNOG; KOG1175; Eukaryota.
DR HOGENOM; CLU_000022_3_5_1; -.
DR InParanoid; G3JC12; -.
DR OMA; IYIMHTS; -.
DR OrthoDB; 144557at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EGX93730.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610}.
FT DOMAIN 43..105
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 111..525
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 590..675
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 736 AA; 79339 MW; E3E58054ED7D1432 CRC64;
MVNAPSKNGT WASASVTPLL SMSRRIALPV VHRRQRTMPH LQDEVLRESL QAPESFWAAQ
AAQLHWHRQP DATLRTSDRT LADGGTPHPD WEWFPGGELS TCYNCVDRHV LAGRGDAVAI
YYDSPVTGTK ETYTYAQLLE QVETLAGALR EEGVKKGDVV MVYMPMIPAA LIGILAINRL
GAVHCVVFGG FAGAALAARI DACKPVLLLT ASCGIDGNKP PIAYRPLVEA ALRLAAHPPR
RTIIWQREQL RWGKTSRVSQ SSWQKWLRSA KERGLRAACV PVGSSDPVYV IHTSGTTGAP
KGVRRDAAGH AVGLHLSMRY LFGVRGPGDV VCTASDIGWV VGHSYIVYAP LLVGAATVLY
EGKPVGTPDA SALWRLVDEY KVSVLFTAPT ALRAIRRDDP HSACLARVGV RGGLRSLRAL
FLAGERSEPR LVQMYQDLLD KYAAQPAAHV IDNWWSTEVG SPMTGRALAP HAAARDDTGD
HALLPPPIRP GSAGKAMPGF DIRVVDDDGQ ELARGSMGNI VLGMPLAPTA FRTLWGDEAR
FHKSYLARFG GRWMDTGDAG MIDDEGYVHV MSRHDDVLNV SAHRLSSGGI EQAVSSHPLV
AECCVVGVPD ALKGQLPFAF ITLSTGGDAH PVSAMPEAGV AAEIQALVRA QVGAIATLGG
IVQGRGVIPK TRSGKTLRRV LRELVDNAVH GDFDREVTVP STVEDPAAVE VARAKIREYF
ETMGHKHKPV EAKAKL
//
