ID G3JJ96_CORMM Unreviewed; 507 AA.
AC G3JJ96;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
DE AltName: Full=Phenylalanyl-tRNA synthetase alpha subunit {ECO:0000256|ARBA:ARBA00030612};
GN ORFNames=CCM_06198 {ECO:0000313|EMBL:EGX92038.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX92038.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX92038.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX92038.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Phe-tRNA synthetase alpha subunit type 2 subfamily.
CC {ECO:0000256|ARBA:ARBA00006703}.
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DR EMBL; JH126402; EGX92038.1; -; Genomic_DNA.
DR RefSeq; XP_006671402.1; XM_006671339.1.
DR AlphaFoldDB; G3JJ96; -.
DR STRING; 983644.G3JJ96; -.
DR GeneID; 18168213; -.
DR KEGG; cmt:CCM_06198; -.
DR VEuPathDB; FungiDB:CCM_06198; -.
DR eggNOG; KOG2784; Eukaryota.
DR HOGENOM; CLU_025086_2_0_1; -.
DR InParanoid; G3JJ96; -.
DR OMA; QIEGWVM; -.
DR OrthoDB; 4619at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR Gene3D; 1.10.10.2320; -; 1.
DR Gene3D; 1.10.10.2330; -; 1.
DR Gene3D; 3.30.1370.240; -; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004529; Phe-tRNA-synth_IIc_asu.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR InterPro; IPR040725; PheRS_DBD3.
DR NCBIfam; TIGR00468; pheS; 1.
DR PANTHER; PTHR11538:SF40; PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF18553; PheRS_DBD3; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:EGX92038.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000313|EMBL:EGX92038.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610}.
FT DOMAIN 225..500
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 507 AA; 57160 MW; 719C2C819BE15822 CRC64;
MATSGDLATQ ILLALSTQSP ILTAEAFPAL ASQDVKAALD RLASRSMITY ETIEREEAVL
EPEAEQIAEH GSHEARVFEA LRKALDGLSV QELEAAIGDK NVTKLGQGKA FREKWIGKNK
DGKLVATADS IQDVTRTQLQ KIKEDRTGDA KTITDLKKRK LIKMQKITSF KADKGPKFAL
EIQKEETDLT SEMITSGAWK TANFKPYNFK ALGADQHAGA LHPLNKVRHE FRQIFFEMGF
EEMPANKFVE TGFWNFDALF VPQQHPARDL QDTFYISDPK VADRPRPQEP GQDTDAYWNN
VKEVHQDGKY GSIGYRYPWA ADESLRLVLR THTTSISAAL LHKLASQKGP DGRPPPARYF
SIDRVFRNET VDATHLAEFH QVEGVIADYG LTLGGLMEFM EIFFGKMGIT DLKFKPAYNP
YTEPSMEIFS YHKGLGKLVE IGNSGMFRPE MLEAMGLPKD MRVFGWGLSL ERPTMIKYKI
SNIRELLGHK VDLNFIERNP AVRLDKE
//
