ID G3JM64_CORMM Unreviewed; 910 AA.
AC G3JM64;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Rad4 family protein {ECO:0000313|EMBL:EGX90788.1};
GN ORFNames=CCM_07208 {ECO:0000313|EMBL:EGX90788.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX90788.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX90788.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX90788.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
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DR EMBL; JH126403; EGX90788.1; -; Genomic_DNA.
DR RefSeq; XP_006672409.1; XM_006672346.1.
DR AlphaFoldDB; G3JM64; -.
DR STRING; 983644.G3JM64; -.
DR GeneID; 18169219; -.
DR KEGG; cmt:CCM_07208; -.
DR VEuPathDB; FungiDB:CCM_07208; -.
DR eggNOG; KOG2179; Eukaryota.
DR HOGENOM; CLU_003639_0_2_1; -.
DR InParanoid; G3JM64; -.
DR OMA; TWPGKTK; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610}.
FT DOMAIN 584..640
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 642..705
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 712..786
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 45..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..880
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 910 AA; 102593 MW; 06BE39F7AD0F4025 CRC64;
MPPHIPRKRL RSASPDVKPQ NKRKPTLYDD LDASTASNSA QATSAFFTNS SDSDISSLSS
LSDDDFEDVP VAKRVSVNDQ GAGNDESDDD AEFEDVVAPE MPTDDLPNVT QDLELTLVRD
DRVSLTNPFG EKRGPTKRER LVRNATHRLH VLCLLWHNAV RNSWLCDPEL QAIMLSHLPP
RMWDEVDRWK EKSGLVRPKP GKSPVKSNGK RKRRSDTKAR DWAADAERLE EGVPDLSNGD
PLFRLGQTIL AWWKQRYRTT TPGLRKWGYM ALERLDRLTK AYASEEKHSP KFGERLENID
DLRQCAARCQ GSRDVGAYLF TALLRALGLE SRLVTNLQCL GYSWTKMEDA AAEQPDSDLR
ARAADLTPKK QAKTKQRSRE LPKQNKPVKP ARKQGVNDAQ LEVEYTDSDD ESVVDMQVTP
VKSKKQPHSH IDADLPYANY WTEVLSPVTG NFLSIEPIVK GIVATNRELV ESLEPRGAKA
DNARQIIAYV VAYSSDGTAK DVTVRYLKQR VFPGRTKGAR YPIEKIPIYN KHGKIHKHKH
HDWFKSAMSG YRRGDKKRPI TDIDETEETT DLQAAKPEKK PVLEGEETLQ YYKQSKEFAL
ERHLKREEAL RIGAKAVKKF QNKGKGNIGE EDVYLRSDVL NVKSAETWHK QGRAPLDGEE
PLKRVPYRAA TTNRRRELLE VEAATGQKVL QGLYSYDQTD WIIPDPIKDG VIPKNEYGNI
DLFAEHMCPR GAVHVPFKGT VRVCKKLGVD YAEAVVGFEF GNRMAVPVIQ GVVIAEENHD
IVMEQLQQDE AERLRKEDEK RRKAALAQWR KFIMGMRIVQ RIRLEYGEID DKTSVFGHGT
KTAPAGAPDA SHAPISNGDE DMAGGFLPEG YEEEDGEEGD GGQQSTSHFF PVVDENEAAE
EGDLVLEHNG
//
