ID G3M6L9_9CARN Unreviewed; 255 AA.
AC G3M6L9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Sphingosine-1-phosphate receptor 1 {ECO:0000313|EMBL:AEO94926.1};
DE Flags: Fragment;
GN Name=EDG1 {ECO:0000313|EMBL:AEO94926.1};
OS Odobenus rosmarus (walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9707 {ECO:0000313|EMBL:AEO94926.1};
RN [1] {ECO:0000313|EMBL:AEO94926.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21940861; DOI=10.1126/science.1211028;
RA Meredith R.W., Janecka J.E., Gatesy J., Ryder O.A., Fisher C.A.,
RA Teeling E.C., Goodbla A., Eizirik E., Simao T.L., Stadler T., Rabosky D.L.,
RA Honeycutt R.L., Flynn J.J., Ingram C.M., Steiner C., Williams T.L.,
RA Robinson T.J., Burk-Herrick A., Westerman M., Ayoub N.A., Springer M.S.,
RA Murphy W.J.;
RT "Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on
RT mammal diversification.";
RL Science 334:521-524(2011).
RN [2] {ECO:0000313|EMBL:AEO94926.1}
RP NUCLEOTIDE SEQUENCE.
RA Meredith R., Janecka J., Gatesy J., Ryder O., Fisher C., Teeling E.,
RA Goodbla A., Eizirik E., Simao T., Stadler T., Rabosky D., Honeycutt R.,
RA Flynn J., Ingram C., Steiner C., Williams T., Robinson T., Burk A.,
RA Westerman M., Ayoub N., Springer M., Murphy W.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; JN633248; AEO94926.1; -; Genomic_DNA.
DR AlphaFoldDB; G3M6L9; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR004061; S1P_rcpt.
DR PANTHER; PTHR22750; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR22750:SF16; SPHINGOSINE 1-PHOSPHATE RECEPTOR 1; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00642; EDG1RECEPTOR.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01523; S1PRECEPTOR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR604061-50};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..204
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT DISULFID 77..84
FT /evidence="ECO:0000256|PIRSR:PIRSR604061-50"
FT DISULFID 175..180
FT /evidence="ECO:0000256|PIRSR:PIRSR604061-50"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEO94926.1"
FT NON_TER 255
FT /evidence="ECO:0000313|EMBL:AEO94926.1"
SQ SEQUENCE 255 AA; 28810 MW; F0CACBC1583C7DF5 CRC64;
TTYKLTPAQW FLREGSMFVA LSASVFSLLA IAIERYITML KMKLHNGSNS FRSFLLISAC
WVISLILGGL PIMGWNCISV LYNCSTVLPL YHKHYILFCT TVFTLLLLAI VILYCRIYSL
VRTRSRRLTF RKNMSKASRS SEKSLALLKT VIIVLSVFIA CWAPLFILLL LDVGCKVKTC
DILFRAEYFL VLAVLNSGTN PIIYTLTNKE MRRAFIRILS CCKCPSGDSA GKFKRPIIAG
MEFSRSKSDN SSHPQ
//
