ID G3N275_BOVIN Unreviewed; 699 AA.
AC G3N275;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=MACPF domain-containing protein {ECO:0000259|PROSITE:PS51412};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000055984.2, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000055984.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000055984.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000055984.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000055984.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3N275; -.
DR SMR; G3N275; -.
DR STRING; 9913.ENSBTAP00000055984; -.
DR PaxDb; 9913-ENSBTAP00000055984; -.
DR Ensembl; ENSBTAT00000063276.2; ENSBTAP00000055984.2; ENSBTAG00000045939.2.
DR VEuPathDB; HostDB:ENSBTAG00000045939; -.
DR eggNOG; ENOG502QRKR; Eukaryota.
DR GeneTree; ENSGT00390000008048; -.
DR HOGENOM; CLU_023578_1_0_1; -.
DR InParanoid; G3N275; -.
DR TreeFam; TF331165; -.
DR Proteomes; UP000009136; Chromosome 15.
DR Bgee; ENSBTAG00000045939; Expressed in placenta and 23 other cell types or tissues.
DR ExpressionAtlas; G3N275; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd22579; MPEG1_P2; 1.
DR InterPro; IPR020864; MACPF.
DR InterPro; IPR039707; MPEG1.
DR PANTHER; PTHR31463; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR PANTHER; PTHR31463:SF5; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
DR PROSITE; PS51412; MACPF_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..699
FT /note="MACPF domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018765465"
FT TRANSMEM 629..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..341
FT /note="MACPF"
FT /evidence="ECO:0000259|PROSITE:PS51412"
FT REGION 679..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 75997 MW; B5AF651152925217 CRC64;
TNLFLNFILL WYIASLGLGH TGDPSGCESC KQQLNVSVLG ALPGAGWDNL RNLELGLVLG
RAYSQCLTTE DGEYLIPDGM LAVPRRETVV QTRADLMDSW VNYTDAWAAS VNAEFSFLSF
LNGKFSAECQ NVRRYSLQYQ TITTRVQRRH SIYSVRVRGT PDFHPDFRQR LLTLSDHLEN
NQTREAEYLA EMLVFAYGTH VLTEVEVGAT LVQEDQVSRE LVGNEDKDRL NVTFAASVLF
DRKVGVGDAV SWDKESQLVQ AYQRGTVASK IHSRGGPPFY EGLTLQKWQE GVANRLVAIG
RSGLPLPALL QPEALPELPA PAVRRVEAAV SRAIGRYYEV NMHPGCVKRG APNFDPLANV
DDGSCTDGQH ANFSFGGVFQ ECEAITGPEG GRLCKPYTIL NPLTGQTSCP ANYTASLLSS
EVKVWSERSY QCWPQCQSCW LIFTCCHRMC GNLEIQRVVR VNASWCAPSG ATPTAAPGLL
FGGLYSPGRP NPRTGAQACP SSFFPLTLLG DLKVCVSSDW ELGVAHAVPF GGFFSCQVVF
NLSVTMDHPM TCPAGYSQHP QLMIRLPPFA ARPSLLGNSS GLGVSVLVDA SGQRAWVKLQ
GSSRWRQADI HDPSVAAQLR DQGGSQPSAG AVVGACLGAV LGVVALALGV TWGFRRYQKR
GYRRLPEGIL AEEQTVYGTA ETAESPAPSD CSENASNSV
//
