ID G3N3D4_BOVIN Unreviewed; 326 AA.
AC G3N3D4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Potassium channel tetramerization domain containing 12 {ECO:0000313|Ensembl:ENSBTAP00000056437.1};
GN Name=KCTD12 {ECO:0000313|Ensembl:ENSBTAP00000056437.1,
GN ECO:0000313|VGNC:VGNC:30502};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000056437.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000056437.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000056437.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000056437.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000056437.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005194239.1; XM_005194182.3.
DR RefSeq; XP_005213929.1; XM_005213872.3.
DR AlphaFoldDB; G3N3D4; -.
DR SMR; G3N3D4; -.
DR STRING; 9913.ENSBTAP00000056437; -.
DR PaxDb; 9913-ENSBTAP00000056437; -.
DR Ensembl; ENSBTAT00000001854.5; ENSBTAP00000056437.1; ENSBTAG00000001414.5.
DR GeneID; 616416; -.
DR KEGG; bta:616416; -.
DR CTD; 115207; -.
DR VEuPathDB; HostDB:ENSBTAG00000001414; -.
DR VGNC; VGNC:30502; KCTD12.
DR eggNOG; KOG2723; Eukaryota.
DR GeneTree; ENSGT00940000161074; -.
DR HOGENOM; CLU_057051_0_1_1; -.
DR InParanoid; G3N3D4; -.
DR OMA; DHGMSDR; -.
DR OrthoDB; 2912088at2759; -.
DR TreeFam; TF315332; -.
DR Proteomes; UP000009136; Chromosome 12.
DR Bgee; ENSBTAG00000001414; Expressed in neutrophil and 103 other cell types or tissues.
DR GO; GO:0045211; C:postsynaptic membrane; IBA:GO_Central.
DR GO; GO:0042734; C:presynaptic membrane; IBA:GO_Central.
DR GO; GO:0043235; C:receptor complex; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd18397; BTB_POZ_KCTD12_Pfetin; 1.
DR CDD; cd22217; H1_KCTD12; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14499:SF29; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD12; 1.
DR PANTHER; PTHR14499; POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:G3N3D4};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 33..136
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 326 AA; 35723 MW; B5C8E815CE0F40C0 CRC64;
MALADSTRGL PNGGGGGGSG SSSSSAEPPL FPDIVELNVG GQVYVTRRCT VVSVPDSLLW
RMFTQQQPQE LARDSKGRFF LDRDGFLFRY ILDYLRDLQL VLPDYFPERS RLQREAEYFE
LPELVRRLGA PQQPGPGPPP PHSRRGVQKE GSLGDDLLPL GSAESEQQEG ASAGAPSPTL
ELASRSPSGG AAGPLLTPSQ SLDGSRRSGY ITIGYRGSYT IGRDAQADAK FRRVARITVC
GKTSLAKEVF GDTLNESRDP DRPPERYTSR YYLKFNFLEQ AFDKLSESGF HMVACSSTGT
CAFAGSTDQS EDKIWTSYTE YVFCRE
//
