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Database: UniProt
Entry: G3N4V8_GASAC
LinkDB: G3N4V8_GASAC
Original site: G3N4V8_GASAC 
ID   G3N4V8_GASAC            Unreviewed;      2602 AA.
AC   G3N4V8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   22-NOV-2017, entry version 33.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor, type 3 {ECO:0000313|Ensembl:ENSGACP00000000328};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000000328, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000000328}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000000328}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSGACP00000000328}.
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DR   STRING; 69293.ENSGACP00000000328; -.
DR   Ensembl; ENSGACT00000000328; ENSGACP00000000328; ENSGACG00000000253.
DR   eggNOG; KOG3533; Eukaryota.
DR   eggNOG; ENOG410XR97; LUCA.
DR   GeneTree; ENSGT00760000119152; -.
DR   InParanoid; G3N4V8; -.
DR   OMA; VVVFYND; -.
DR   TreeFam; TF312815; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt-bd.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007635};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2194   2217       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2429   2452       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      114    174       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      175    225       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      233    289       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      296    374       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      380    436       MIR. {ECO:0000259|PROSITE:PS50919}.
SQ   SEQUENCE   2602 AA;  295487 MW;  EF7E09E667EE1D42 CRC64;
     MSDSASSFLH IGDIVSLFAE GSVNGFISTL GLVDDRCVVE PAGGDLENPP KKFRDCLFKV
     CPMSRYSAQK QFWKAKQAKH EKDKIADVVL LQKLQHASNL EQKQNETENK KVHGDVVKYG
     TVLQLLHMKS NKYLTVNKRL PALLEKNAMR VTLDGTGNEG SWLFIQPFWK LRANGDNVVV
     GDKVILNPVN AGQPLHASNY ELSDHPGCKE VNSVNCNTSW KINLFMMFSD HREEVLKGGE
     VVRLFHAEQE KFLTCDEYKS RNHVFLRTTL RQSASSATSS NALWEIEVVH HDPCRGGAGH
     WNSLYRFKHL ATGNYLAAEE NPGYKGDHAE PASSVSLLMD SRSIKRSHGE RIKYKLVAVA
     HGSDIASLFE LDPTTLQKTD SFVPRNSYVR LRHLCTNTWI QSTNVPIDID EERPIRLMLG
     TCPTKEDKEA FAIVSVPVME IRDLDFANDA SAMLSTVVEQ FSQGFISQND RRFAIKLLED
     VVFFVADVIN SGQAVLDVVM TKANRERQKL MREQNILKQI FGILKAPFKD RGGGEGPLLR
     LEELADQKNS PYQYMFRLCY RVLRHSQEDY RKNQEHIAKQ FGVMQSQIGY DILAEDTITA
     LLHNNRKLLE KHITKTEVET FVSLVRKNRE PRFLDYLSDL CVSNNIAIPV TQELICKCVL
     EPKNQDILIK TERRVPKDAP TGGGQADYLG MDDYGDEDEV WLVWTDKTNE RQEKGIRQLA
     QEARQGNAHD ENVLTYYRYQ LKLFARMCLD RQYLAIDEIS KQLDVELIFL CMMDETLPFD
     LRASFCRLML HAHVDRDPQE LVTPVKFARL WTEIPTSITI KDYDSNMDDS RDNKKNRFSN
     TMVFMEEYLN NVLNDELPFH NEEKNKLTYE VVSLARHLIY FGFYSFFELL RLTRTLLGII
     DCRPHPGYNG LLFHDDGSGK NVKRSIHGMG QMMSTMVLNR KQSLFGGAGA RGAGVGAGLA
     IDGQRGSKDS IDKMDLTVMD TKLKILEILQ FILNVRLDYR LSFLLSVFKK EFVDVYPMAD
     ADATTNMEHA ATINLQHIGE QAEAMFGVGK GNSILEVDDE GGRMFLRVLT HLTMHDYPPL
     VSGALQLLFR HFSQRQEVLH TFKQVQLLIS AQDVENYKLI KADLDRLRTL VEKSELWVEK
     KSSGGGDGKK DKKDKGQDMQ EKGNENYQKV KEILERLNKM CSTGVWKKQQ RLLKNMGAHK
     VMLDLLQVSY DLNDVKMQEI IRYTHLFLQK FCTGNQENQT LLHKNLSLFL NPGLLEAETV
     QHIFCNNYQL CSEISESVLQ HFIHCLATHG RHVQYLNFLH TIIKAEGKYV KKCQDMIMTE
     LTNAGEDVVV FYNDKASFNV MLELMAESRE GVGDSSPLRY HISLVELLAA CAEGKNVYTE
     IKCTSLLPLE DVVRVVTHED CITEVKVAYV NFVNHCYVDT EVEMKEIYTS NHIWNLFEDF
     TVDMARVCNK REKRLSDPIL EKYIINVVFD TINAFFSSPF SENSTSLQTH HTIVTHLLQS
     SVRVLDCPWL RHQGGQVETC IKTLAMTGNC RSISLPLDLE AQISIMLSSP ALNSLSRSNP
     NYKSPSRSSR PVAPSNPWDY KNIIEKLQDI INTLEERLKP LVNAELSVLV DVLHQPELLF
     QEGTDARQRC ESGGFISKLI QHTKALMSAE EKLCIKVLRT LQEMLIRTLD FDEKVLLQIY
     LFPNKKNHVK TELAELGSPR ERDWAAVASV QCRLDREGGT KLFTDLVMSS KNDKIFQESI
     QLAICLLEGG NTEIQNSFYK LMMGDNKSEK FFKVLHERMK EAQTDIKATV SVNVGEMTHK
     ASEKDLEPGE TGGSAALVLP GTGSHPLLAQ SIAPVASALP VPPAVEQREV EMEMGPAVTI
     MKPILRFLQL LCENHNHDLQ NFLRCQNNKT NYNLVCETLQ FLDIMCGSTT GGLGLLGLYI
     NESNVHLITQ TLETLTEYCQ GPCQENQTCI VTHESNGIDI ITALILNDIS PLCRYRMEMV
     LQLKDNASKL LLALMESRHD SENAERILFN LRPRELVEVI KKAYQQDSEC EGGEVSPREV
     GHNIYILAQQ LARHNKLLQN LLKPQKNSKE GEEGISSMLN NLNNRPLSQM LKSSTPAAVV
     EQDPLEYYDL LTSQIEIVRD DRSMEQIVFP VHPICEFLTE ESKTRVFNTT EQDEQGSKVT
     HFFEQTSFLH GEMEWQKKLR SMPVLYWFSG RMSLWGTISF NLAVFINLII AFFYPYASGQ
     GTAGTTSTTS TTILKTCCYT KPEIITILLL PYLRPLLYVA CHNNTWNRVN NLCSVCCSLR
     VNESQVKTFQ HITAQHEPEI VLVQTFQARS PGFSCLFCFV VLKVRLTALS AGINTFQRCV
     NVSGSAYSLG PPLDSYPPVG RHSMDSLAAD AVSGILAGPP GPWRACDTLL MCIVTVLNHG
     LRNGGGVGDV LRKPSKNEPL FAARVVYDLL FYFIVIIIVL NLIFGVIIDT FADLRSEKQK
     KEEVLKTTCF ICGLERDKFD NKTVSFEEHI KLEHNIWNYL YFIVLVREKN KTDYTGPESY
     VAHMIKNNNL DWFPRMQAMS LVVTDGDGEQ NEMRMLQDKL ASTMKVVITL TTQLTELKEQ
     MTEQRKRRQR MGFADHQSGA GA
//
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