ID G3N5T5_GASAC Unreviewed; 386 AA.
AC G3N5T5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Sorting nexin family member 21 {ECO:0000313|Ensembl:ENSGACP00000000659.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000000659.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000000659.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000000659.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004469}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004469}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004469}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR AlphaFoldDB; G3N5T5; -.
DR STRING; 69293.ENSGACP00000000659; -.
DR Ensembl; ENSGACT00000000659.1; ENSGACP00000000659.1; ENSGACG00000000515.1.
DR eggNOG; KOG2101; Eukaryota.
DR GeneTree; ENSGT00530000063759; -.
DR InParanoid; G3N5T5; -.
DR OMA; DQMERVC; -.
DR TreeFam; TF326807; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000000515; Expressed in zone of skin and 12 other cell types or tissues.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR039937; SNX20/SNX21.
DR PANTHER; PTHR20939; SORTING NEXIN 20, 21; 1.
DR PANTHER; PTHR20939:SF10; SORTING NEXIN-21; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 130..247
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 16..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..46
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 386 AA; 43305 MW; 0A06B9C701BC4FE7 CRC64;
MASRLLYRLK RSLFKDGQGA GPEQESACGQ EVEDGWEAEL EEEEEERVTD RLGGTLSFHA
GGGEGVEDGS EELDSDSDYL GESMEEGLSS TAPVAPPTSF LLTRQLQESW RTLRGLGGGS
PASTGRQPTD DLLFEVTDAS VVQDASSKYV LYTIHVVQSA GSDKTPAVIT CRYSDFQRLH
AALRRDHGDQ MGRVCFPRKK LRRNYTAETI GKRSRAFEQY LSHLCSLSGP RGAPCVRHFF
YLADLQAGQL LIRVGRFQEA LGPLLNAKRL QEKLGWATYY DRRAPPPASS HWLFTLVGLL
SCFQEVDQLE EARDHCDDAL RVLSPETARP HPLLLPLLRV VVRLSWQTGK DKRQWEELLQ
KLEEQRAGLV DNHPTIKEFL VKHNLE
//
