ID   G3N6X9_GASAC            Unreviewed;       623 AA.
AC   G3N6X9;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=Menin {ECO:0000256|ARBA:ARBA00021162};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000001054.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000001054.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000001054.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; G3N6X9; -.
DR   STRING; 69293.ENSGACP00000001054; -.
DR   Ensembl; ENSGACT00000001054.1; ENSGACP00000001054.1; ENSGACG00000000817.1.
DR   eggNOG; ENOG502QUYK; Eukaryota.
DR   GeneTree; ENSGT00390000014237; -.
DR   InParanoid; G3N6X9; -.
DR   OMA; SDVIWNG; -.
DR   TreeFam; TF323888; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000000817; Expressed in embryo and 12 other cell types or tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd14456; Menin; 1.
DR   InterPro; IPR007747; Menin.
DR   PANTHER; PTHR12693; MENIN; 1.
DR   PANTHER; PTHR12693:SF3; MENIN; 1.
DR   Pfam; PF05053; Menin; 2.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          377..400
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          458..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          594..623
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..492
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..510
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        594..612
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  68913 MW;  F423570C1539B9FB CRC64;
     MGLHSAQKKH FPLRGIDGVV QLFDAELRKS EPDLALLSLV LGFVEHFLAV NRVIPINVPG
     VRFEPLEPDC PNSCFPTVEL GMISALYERF TAQIRGAVDL SQYRKTASGS SRELVKKVSD
     VIWNSLSRSY FKDRAHIQSL FSLITGTKLD SSGVAFAVVA ACQVLGLKDV HLALSEDHAW
     VIFSKNGEET AEVTWHGKGN EDRRGQTVAA GVSEKSWLYL KGSYMKCDRN MEVAFMVCAI
     NPSLDLHTDS SELLRLQQKL LWLLYDRGDL DRYPMAMGTL ADLEDQDPIP GKESPMTIHL
     KAVSSAQKHY NNEHIYPYMY LAGFHYRHRD VREALGAWAE AAQVMQEYNY FREDEEIYKE
     FFDIANDVIP TLLKETAAAA ESPGEGGEGA DKEHPKQAAA LSALQDPECF AHLLSFYDGI
     CKWEEGSPTP VLHVGWATYL VQSLSRFDAQ VRQKVSIVIK EPESQDDDDM SSEDPREGRR
     RGPRRESKLD EQGPFPPDGP TSPSSQPPAA AAPQPKKIGE GGGRRRSSQG LRPGDADGKP
     KSPSPDSSPS PQQQASPCPA GPVVAFQSEK MKGMKGLLCA AKVNSSAIKL QLTAQSQVQM
     KRQKSTPAGD YSMSFMKRQR KSL
//