ID G3NK29_GASAC Unreviewed; 759 AA.
AC G3NK29;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Pyridoxal-dependent decarboxylase domain containing 1 {ECO:0000313|Ensembl:ENSGACP00000005691.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000005691.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000005691.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000005691.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR AlphaFoldDB; G3NK29; -.
DR STRING; 69293.ENSGACP00000005691; -.
DR Ensembl; ENSGACT00000005707.1; ENSGACP00000005691.1; ENSGACG00000004296.1.
DR eggNOG; KOG0630; Eukaryota.
DR GeneTree; ENSGT00390000009628; -.
DR InParanoid; G3NK29; -.
DR OMA; PEHSQYG; -.
DR TreeFam; TF313101; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000004296; Expressed in intestinal epithelial cell and 12 other cell types or tissues.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR42735; -; 1.
DR PANTHER; PTHR42735:SF1; PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT REGION 661..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 759 AA; 83368 MW; F7B22EE312780CA7 CRC64;
MVNSTFAQVG KNLSEAMRIL GDGQIEPEAG PVKWRFNRTT IPGPLQGDGQ DVATILHLVH
NLIHDEEEEE DDNRMQHVGE QGHMALLGHS LAAYISVLDR ERLRKLTTRI LSDTTLWLCR
LFRYENGSAY FHEDDRDGLV KVCRLVINAR YEEYASEGYS VLGSRQPVIY QSASGRPGLG
QHLCSQLGLP LSSLCTVPCN TIFGSQHQMD IALLDKLIKE DIEARKLPLL LVANAGTPGA
GHTDKLARLK DLCDQYSMWL HVEGVNLATL ALGQVTSAIM AASRSDSMTL TPGQWLGLPA
VTAVTLYRHE DPALSLAAGL TSSQPVAKLR ALPLWLSLQY LGHSGIVQKI RHSTALTQQL
LPKLKTLASI KTLVEDELSS PVVLFRFSQE ISSASSGGSV EGHCAGEKEV LDAFNRWLGE
QLLQLVPTSG VDVVELEDEG TCVRFSPLLT AEVLGTQEEN IVDIMEKLSE LVSVMCSTMC
LRQDFREESH RHSPSLSYVQ QLSWPGLGAV RYEPRAEGMD ESRRKQEMQK INSELLKKLQ
DLETDIIFST GPEFGTEEDC IFVGMVTEDV DVSELVDTLA SLGRDIEESG RLLDNMTEVV
RKGILEAELQ LQKANEEKLM EEGALRQLPL VGSVLNWFSP SQSSIKGRTF NLAAGSLDST
ETTYSTKAQP GRPSLQDSST SLRKQPGQRL FRRSGAGSDS FSETSSIGPA EETTRDTSAI
PSESINPPAS HPVVQLEDGG ASEERVPDGQ EVEQKENVR
//
