ID G3NNK1_GASAC Unreviewed; 382 AA.
AC G3NNK1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=General transcription factor IIA, 1 {ECO:0000313|Ensembl:ENSGACP00000006915.2};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000006915.2, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000006915.2, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000006915.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
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DR AlphaFoldDB; G3NNK1; -.
DR STRING; 69293.ENSGACP00000006915; -.
DR Ensembl; ENSGACT00000006932.2; ENSGACP00000006915.2; ENSGACG00000005224.2.
DR eggNOG; KOG2652; Eukaryota.
DR GeneTree; ENSGT00940000156726; -.
DR InParanoid; G3NNK1; -.
DR OMA; EVCDASQ; -.
DR TreeFam; TF350445; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000005224; Expressed in intestinal epithelial cell and 13 other cell types or tissues.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd07976; TFIIA_alpha_beta_like; 2.
DR Gene3D; 1.10.287.100; -; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR12694; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR PANTHER; PTHR12694:SF7; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR Pfam; PF03153; TFIIA; 2.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT REGION 252..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..333
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 42173 MW; C61DEEB9FEC67DBE CRC64;
MASSANSNPV PKLYKSVIED VINEVRELFL DEGVDEQVLL ELKTLWENKL LQSKAVEGFH
TEEQAALQAA QQQQQQHQVQ QVQQVQQVQQ QVQQVHQVQQ VNQPAQAQQV ILPPQQQQAQ
QQVIVQDSKI LQHMSATGMQ SAAATAATLA LPTGVTPYQQ LITSQGQILQ VVRAANGAQY
IIQPQQQILV QQQMQPGSVQ APVIQQLCVQ VLAPMQGGLS QQGVIIQPQQ IVLASGNKVQ
GNPQVRTASV PVQQVQGSAA PQVPAQTQAQ QPPMILQADG AGDTSSEDDQ DDEEEEYGED
EEEEKDKDGG EDGQVEEEPL NSSDDVSDEE DQELFDTENV VVCQYDKIHR SKNKWKFHLK
DGIMNLNGRD YVFSKAIGDA EW
//
