ID G3NP43_GASAC Unreviewed; 264 AA.
AC G3NP43;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=SEBOX homeobox {ECO:0000313|Ensembl:ENSGACP00000007107.1};
GN Name=SEBOX {ECO:0000313|Ensembl:ENSGACP00000007107.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000007107.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000007107.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000007107.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC developmental regulatory system that provides cells with specific
CC positional identities on the anterior-posterior axis.
CC {ECO:0000256|ARBA:ARBA00003263}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR AlphaFoldDB; G3NP43; -.
DR STRING; 69293.ENSGACP00000007107; -.
DR Ensembl; ENSGACT00000007125.1; ENSGACP00000007107.1; ENSGACG00000005381.1.
DR eggNOG; KOG0849; Eukaryota.
DR GeneTree; ENSGT00920000149180; -.
DR InParanoid; G3NP43; -.
DR OMA; YQAFRNF; -.
DR TreeFam; TF315976; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR042223; SEBOX.
DR PANTHER; PTHR47777; HOMEOBOX PROTEIN SEBOX; 1.
DR PANTHER; PTHR47777:SF1; HOMEOBOX PROTEIN SEBOX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 16..76
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 18..77
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 264 AA; 29078 MW; 2F354513FB22B48F CRC64;
SSPEPDRPAA FGPMEGQRKR KRTIFSRAQL TELEQAFAVT PYPDITLRER LAAHTHLPES
KIQVWFQNRR ARSIKTVRLP KSSQPALGGR GVVDPSTGQV TAAFLSSTTL ADIFRPEQNH
SCEDVPQIYS DWFQIYSNPV SSPASSSSLQ PTPGSSKPSE RYLWEEDRPP HHSASARSYQ
AFRNFKPQSA PPSGPHQAAY GGGAAGGGHT SVDQVVPSHP QPVYWEVAQA QGHHHHPQMG
PQTSMGYISD LIYNAAIVTN FLEF
//
