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Database: UniProt
Entry: G3NYR5_GASAC
LinkDB: G3NYR5_GASAC
Original site: G3NYR5_GASAC 
ID   G3NYR5_GASAC            Unreviewed;      1214 AA.
AC   G3NYR5;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   25-OCT-2017, entry version 37.
DE   SubName: Full=Si:ch211-173d10.1 {ECO:0000313|Ensembl:ENSGACP00000010486};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000010486};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000010486}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000010486}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSGACP00000010486}.
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DR   Ensembl; ENSGACT00000010508; ENSGACP00000010486; ENSGACG00000007901.
DR   eggNOG; ENOG410INBV; Eukaryota.
DR   eggNOG; ENOG410YW28; LUCA.
DR   GeneTree; ENSGT00760000119127; -.
DR   OMA; GQAPWSD; -.
DR   TreeFam; TF314204; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:InterPro.
DR   GO; GO:0061337; P:cardiac conduction; IEA:InterPro.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:InterPro.
DR   GO; GO:0002724; P:regulation of T cell cytokine production; IEA:InterPro.
DR   GO; GO:0042310; P:vasoconstriction; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR029581; TRPM4.
DR   PANTHER; PTHR13800:SF6; PTHR13800:SF6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007635};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    778    805       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    867    889       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    901    921       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    933    951       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1024   1046       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      792   1060       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1214 AA;  138137 MW;  FDFFE62ED6581660 CRC64;
     HVGKSEKDQS WIPKIIKKRV CTTFVEDSVS NGALCQCGGK RDDHGSVALG DYFSTAIVNR
     WDSVQHSSEY PTDAFGELQF AGASKRHSYF LRLSWDTPPS MVYTLMTAHW HLPAPNLVVS
     IVGGEGRTKV KTWVREVLRQ GLVKASQSTG AWILTEGLRE GVGRCVGEAV RDHATAASSV
     SVNKVVALGV APWGLVDNRQ QLVNPEGSFP AKYFVQNKHK DSCRLDNNYQ AFLLVDDGSV
     GRRGETGFRA KLEDYISHQR TGIWGSGSID IPVLCMLISG DAGMLERVDL SLKSSMPWLV
     LAGSGGLADF LSDVLDNLSS ATAVQSSDKV AERVKKHFPA EKEPDKLVER ALSIYQMRDF
     ITVYHGEQEG PNEFDTVLLK TLVGASKHRA SVDASPYNEE LKLAVTWNRV DIAKSELFNG
     DIPWTYEDLE DPMTDALIND KPQFVRLFTE NGLNILDYLT YGRLESLYSS VAEGTVLYHL
     LQRQLVERLG TATSNQQDLP SKLAAENVAR VLELLMGDVC QPFYYNALGL EDISSKRKAL
     RVPSLFTQRV SKVLRGECSY RKEQCQSPWT SLFIWAVLQN RSEMATFFWE MAGESVLSAL
     SGCKILREVS KLEVETENKL SMKELAQRFE NLAHDMFSSC YRSNESRSFT LLIRKSTVWG
     ATTCLQMGMG ADARLFFSHD GVQSLLSQIW WGDMKRNTDV WKLLLTFFCP VLCYTNLISF
     RKQEDQHEGE DEKPNEDGAA SDADAQESVA PSTPGIKGRR LSHNPPHRPF IVSRWRQFWF
     APVTAFLGNV LMYFLFLLLF AWVLLVDFKP PSSSRLAITE YVLYFWVFTI VCEEIRESLE
     GVDCQVSRRG SETRTWRQRV RVYIQDVWNM CDLITIVLFI VGVICRMFTW SYELGRDAMC
     VDYMVFTVRL IHIFAIHKQL GPKIIIVGKM MKDIFFFLFF LMVWLMAYGV ANQALLYSYD
     PSLERILRHV FYRPYLHIFG QIPVEEMDVS LSVPVGKEWD RLCTDNMTLI ESGQEPCRTL
     YSNWLVVILL VVYLLVTNIL LINLLIAMFS STFSEVQANS DIYWKFQRYT LVVQYHSRPS
     LAPPFIILSH INLFIKRVIR KVPSIKLHHF VLELKGKAAN KLKTWEAIQK EDVLTAQNKI
     QRSSDSERLK RMSVKVDGVF KHVTESRDFD HRLRALENEM EYCSNALSWI VDTLAQGSTF
     KPPRRPPPSR GTNE
//
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