ID G3P0A8_GASAC Unreviewed; 532 AA.
AC G3P0A8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 {ECO:0000313|Ensembl:ENSGACP00000011031.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000011031.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000011031.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000011031.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3P0A8; -.
DR STRING; 69293.ENSGACP00000011031; -.
DR Ensembl; ENSGACT00000011054.1; ENSGACP00000011031.1; ENSGACG00000008338.1.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000159143; -.
DR InParanoid; G3P0A8; -.
DR OMA; DKKEMTY; -.
DR TreeFam; TF330861; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000008338; Expressed in camera-type eye.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF14; LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 215..307
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 471..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..532
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 532 AA; 59645 MW; 9E94E5FC0B1EB546 CRC64;
MEESAFGAIP GNLPDDLNKI RIEKSHFTEI PRGAFSQTPA LENLWLNFND ITLINSKGLQ
GLRNLTELRL QGNKLRSVPW TAFEDTPALK ILDLKHNQLD VLPEHALKFL PDLTYLDLSF
NRLTVISKEV FQNWPLYQKL QNTEEREGPA FGPNVVLALH DNAWVCDCRL KGFVEFIRSL
SPPIILMNSY LTCSGPDFRE GKFFHEVELQ ACVKPVVNTP SPNISLPLGA NLTLRCFAKA
QPNPAVWWTY GLKIIKGFRE SQERVDDNTI RSLLEIPSLR ATDRGVYTCT AVNFIGNSSV
SVLLDVNSPD GSQSSVLSDK PAAPAASDEN VYISIRIAKQ TVRGITIEWH AALERPTETW
FTIHFGSAGN DKKETIFIGP GINSYSVSDL MPATKYEMCV TLKNQAPHNG QCIVFVTGSD
ITEMEQREKL IHIVVIVLAM VLAVPIGMYA CTTDTKCACL EGIIESWKNR RRERNSPGME
RERQGTFDSL QAASDEGLVN KDSSEDRKVR RRSEDRQHKG KADHGRQTAE LY
//
