ID G3P6K5_GASAC Unreviewed; 1145 AA.
AC G3P6K5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Pleckstrin homology domain containing A5 {ECO:0000313|Ensembl:ENSGACP00000013228.1};
GN Name=PLEKHA5 {ECO:0000313|Ensembl:ENSGACP00000013228.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000013228.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000013228.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000013228.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3P6K5; -.
DR STRING; 69293.ENSGACP00000013228; -.
DR Ensembl; ENSGACT00000013253.1; ENSGACP00000013228.1; ENSGACG00000010014.1.
DR eggNOG; KOG0940; Eukaryota.
DR GeneTree; ENSGT00940000155728; -.
DR InParanoid; G3P6K5; -.
DR OMA; AXTESAG; -.
DR TreeFam; TF329090; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000010014; Expressed in liver and 8 other cell types or tissues.
DR CDD; cd13248; PH_PEPP1_2_3; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR040392; PKHA4-7_PH.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR12752; PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN; 1.
DR PANTHER; PTHR12752:SF3; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 5; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 11..44
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 58..92
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 172..271
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 112..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 839..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1117..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 671..698
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 124..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..858
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..947
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1145 AA; 129401 MW; 38636B967A265B01 CRC64;
MAADIQPEWI SGLPSSWSYG VTRDGRVFFI NEEAKSTTWL HPVRGEALIT GHRNTPATDL
PTGWEEGYTF EGARCFINGT NDRKVTFEHP VPNLFPQDNC IFVVHKKSAS KVPANEKKDR
PLSTMTEASN YTGSSDFAAN PTNTAERPSR PSKKIHNFGK RSNSIRRNPS APVIRRNWLY
KQDSTGMKLW KKRWFVLSDL CLFYYRDEKE EGILGSILLP SFRVSMLSVD DHINRKYAFK
ATHPNMRTYY FCSDTAKEME AWMKVMTDAA LVHSEPVKRL DRLKVEQCGP QEINHVADHR
PPLTQPEIHN NQLNREVDRE RAPEASPAAA DDERKQRDAE RYGFQQDGAE RGRPLTKINS
VKLQPAQAAA VKAGVASPQP PTEVDGSHRG PQVNGSGEHA AQDRTAVPPR RSPTPEPDRA
LSRTSSMQQL EHWVRTQRGR NQDDDTRSIT SYQTLPRNMP SHRVPYMPHY GDGYSSMPRN
SMAQRDSLCS MSPSLYEQAL GPSPVDNRRS MRDDTMWQLF EWQQRQAYTR PPPPGLYRDM
ASPKTMINLS EHAAPSHSIP PSPSHGSLSM YGGYSPMRSY VSGAHSEVSS PVYRGDASID
RRVRPQHNKY AYPPDRRSMP AGIPVQTISA QSLHGKTLGP EDYRDLAYAR AAEEVDIDTK
LSRLCEQDKV VRTQEDKLKQ LYREKHTLET ALLSASQEIE MGSESPAAMQ SVIQQRDLLQ
SGLLSTCRER SRIAAELELS WREYEKLEGD VALAKNDLLE QLEALGSPQT EPPSQQHVRI
QKELWRIQDV MEALSNHKAQ READGMSLHE PMTNFSKNKN EGPDYRLYKS EPELTTVAEV
DESNGEDRSE HPSDREHSGN KGSYPVGIVP PRTRSPVTDS SSIASYVTLR KSKRPDPKAE
RPRSALEQQL CAAESGRPRM SVEEQLDRIR RHQQGALREK KKGAHVRGAG QENTPSRSHS
FTKENHYRAQ SQMRRREEGI CCIDELEASL RLQEVVRDQE TPAEEIARLK EASQDDHLNM
DRELSVPDKV LIPERYVESD PEEALSPEQE ADKQRKVDRI KALIAKNSMQ NALPSMALSP
EEETEVEVTV QEKEKMINIS YELAAEASKR SKLVAVNRLS SSSSPLPQPS NTPPQLPDGS
HFMCV
//
