ID   G3P9S3_GASAC            Unreviewed;       821 AA.
AC   G3P9S3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Pre-rRNA-processing protein TSR1 homolog {ECO:0000256|ARBA:ARBA00040070};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000014347.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000014347.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000014347.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Required during maturation of the 40S ribosomal subunit in
CC       the nucleolus. {ECO:0000256|ARBA:ARBA00037087}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Bms1-like GTPase family. TSR1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00038288}.
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DR   AlphaFoldDB; G3P9S3; -.
DR   STRING; 69293.ENSGACP00000014347; -.
DR   Ensembl; ENSGACT00000014372.1; ENSGACP00000014347.1; ENSGACG00000010843.1.
DR   eggNOG; KOG1980; Eukaryota.
DR   GeneTree; ENSGT00940000153195; -.
DR   InParanoid; G3P9S3; -.
DR   OMA; MNLPRFK; -.
DR   TreeFam; TF105717; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000010843; Expressed in embryo and 12 other cell types or tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR012948; AARP2CN.
DR   InterPro; IPR039761; Bms1/Tsr1.
DR   InterPro; IPR007034; BMS1_TSR1_C.
DR   InterPro; IPR030387; G_Bms1/Tsr1_dom.
DR   PANTHER; PTHR12858:SF1; PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG; 1.
DR   PANTHER; PTHR12858; RIBOSOME BIOGENESIS PROTEIN; 1.
DR   Pfam; PF08142; AARP2CN; 1.
DR   Pfam; PF04950; RIBIOP_C; 1.
DR   SMART; SM00785; AARP2CN; 1.
DR   SMART; SM01362; DUF663; 1.
DR   PROSITE; PS51714; G_BMS1; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT   DOMAIN          88..252
FT                   /note="Bms1-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51714"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          424..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..29
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..49
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..67
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        424..459
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   821 AA;  92957 MW;  48BBC0A7C5D2D4EA CRC64;
     MAANEEKQQG HRPGIYKQKN KGHKHGKHRT KGELERENKG RVSVTAFTKK QRKEHKRMDR
     RHKANQLRRN KKDIVLTEKR RLGTRDGPPH LVAVLSLHAG VDAAAVTKLL RGDAAGGVVH
     QERCVSGISD SFGLLLPRFK QRFTFISHST ADIHSLLDVA KIADSLVFVL DSAEGWDSYG
     EYCLSCLFAQ GLPSHALVCQ GVSDLPVKKR VDSRRALSKI TEIRFPDARL FPLDSEQDAT
     LLLRHLGSQR QRKLGFRSRR SHLLAQNVTF TPNCPAEGTG DGPTDLGTLC VSGYIRGRPL
     QVNRLVHISG HGDFQLSQID GPPDPLPLIL TPARPAKPVK EGDVDMLVGC VPQDGGEGEA
     PVRVLVKADL SCRESLQAEA EVDPMDGEQT WPTETELLEA DEAIKNKRVM KVPKGTSDYQ
     AAWILDEEEE NNGDLDEESS EEDDDDDDML DEAMDGEDED NNSQVCSTER TGADQRYDED
     IDKAAEEEGL QRYREARANV MFPDEVDTPL DMPAKIRFQR YRGLKSFRSS PWDPMENLPA
     NYSRIFQFQS FERTRRRILA EAEAEDEGAM VGWYVTLHII DVPFSVMESV HSGRPLVLVS
     LLPHEQKMSV MHLLVRRHPS NTEPIKSKEE LVFHCGFRRF RASPIFSQNA SADKHKMERF
     LKPDAPTVVS VYAPITFPPT GVLLFKQKND GIQDLVATGS LLSCDPRRVT LKRIVLSGHP
     LKINQRSAVV RYMFFNRDDI LWFKPVELRT KWGRRGHIKE SLGTHGHMKC VFDNQLPSQD
     TVLMNLFKRV YPRWTYDPYV PMSLPWVKRE VTVEMDDLDM E
//