ID G3PI27_GASAC Unreviewed; 639 AA.
AC G3PI27;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Heat shock protein family A (Hsp70) member 2 {ECO:0000313|Ensembl:ENSGACP00000017254.1};
GN Name=HSPA2 {ECO:0000313|Ensembl:ENSGACP00000017254.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000017254.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000017254.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000017254.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR STRING; 69293.ENSGACP00000017251; -.
DR Ensembl; ENSGACT00000017285.1; ENSGACP00000017251.1; ENSGACG00000013046.1.
DR Ensembl; ENSGACT00000017288.1; ENSGACP00000017254.1; ENSGACG00000013051.1.
DR Ensembl; ENSGACT00000017296.1; ENSGACP00000017262.1; ENSGACG00000013055.1.
DR eggNOG; KOG0101; Eukaryota.
DR GeneTree; ENSGT00940000154813; -.
DR OMA; KSHIHEI; -.
DR TreeFam; TF105042; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000013046; Expressed in embryo.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10233; HSPA1-2_6-8-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375:SF547; HEAT SHOCK COGNATE 70-KD PROTEIN, TANDEM DUPLICATE 3-RELATED; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT REGION 614..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 70026 MW; 6B22E9BCC5AE78AF CRC64;
MSAAKGTAIG IDLGTTYSCV GVFQHGKVEI IANDQGNRTT PSYVAFTDTE RLIGDAAKNQ
VALNPSNTVF DAKRLIGRKV EDPVVQADMK HWPFKVVGDG GKPKIQVEHK GEEKSFYPEE
ISSMVLVKMK EIAEAYLGHK VSNAVVTVPA YFNDSQRQAT KDAGVIAGLN VLRIINEPTA
AAIAYGLDRG KTGERNVLIF DLGGGTFDVS ILTIEDGIFE VKATAGDTHL GGEDFDNRMV
NHFVEEFRRK HKKDIRQNKR ALRRLRTACE RAKRTLSSSS QASIEIDSLF EGVDFYTSVT
RARFEELCSD LFRGTLEPVE KALNDAKMDK GQIHDVVLVG GSTRIPKIQK LLQDFFNGRE
LNKSINPDEA VAYGAAVQAA ILTGDTSGNV QDLLLLDVAP LSLGLETAGG VMTALIKRNT
TIPTKQTQVF STYADNQPGV LIQVYEGERA MTKDNNLLGK FDLTGIPPAP RGVPQIEVTF
DVDANGILNV SAVDKSTGKE NKITITNDKG RLSKEEIERM VQDADKYKAE DDLQRDRVSA
KNSLESYAFS VSSSLRDENL RGQVSAEDLK KVTEKCEETV AWLENNQLAE KEEYQHKQEE
LEKVCNPVIS KLHQGGRPAA SCGEQARAGS QGPTIEEVD
//
