ID G3PIV1_GASAC Unreviewed; 524 AA.
AC G3PIV1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Glycerophosphodiester phosphodiesterase domain containing 4a {ECO:0000313|Ensembl:ENSGACP00000017530.1};
GN Name=GDPD4 {ECO:0000313|Ensembl:ENSGACP00000017530.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000017530.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000017530.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000017530.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000256|ARBA:ARBA00007277}.
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DR AlphaFoldDB; G3PIV1; -.
DR STRING; 69293.ENSGACP00000017530; -.
DR Ensembl; ENSGACT00000017564.1; ENSGACP00000017530.1; ENSGACG00000013263.1.
DR eggNOG; KOG2258; Eukaryota.
DR GeneTree; ENSGT00940000156251; -.
DR InParanoid; G3PIV1; -.
DR OMA; IFHWRER; -.
DR TreeFam; TF313692; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000013263; Expressed in camera-type eye and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08574; GDPD_GDE_2_3_6; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR23344:SF13; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR23344; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 227..484
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 524 AA; 59268 MW; 01B0FDF6BBBB79AA CRC64;
VVRRQLLQRY EHQPFVSCLA GLYGCQWRRY QRARAQPGEC CCSFGLLILT FFFSFLFLYF
WSEAQNDYID FDWFNFGTLG FWFPWSLVLL VVAAALFTYI ALLLVLAVCL LSEGQRLYLH
WSHKTGIVVV LAFSVIATAI LSDLWSKEWK TLLLSLQVTA PFLHVAAVSL MVVLSWPIAL
HFFRMSKRVR QVAILGLYLS VLSSLYLVPL GMYSPCILEA GRLGPAPTLI GHRGAPMLAP
ENTVMSFERA VEAGGEGLET DVTISYDGVP FLMHDSTLRR TTNVADVFPN RTHVDASMFT
WAELQLLNAG DWFLSRDPFG TVSSLSEADC SMAQNQSVPS LAQFLELAAI SNKFVLFDLH
RPPFGHPYYE SYINTTLQVV QAHINSSQVL WLTSEDRELV QAVDPELQQT SGEGASLQDL
TDGHITRLNL HYSTMSQQQF SKYQSVNIST NLYVISQPWL YTLAWCAGAQ SVTTNSVHIL
SNVNKPLFLM TPEEYSLMWI LTDAVSAFLI IAVFIFHWWR ERGL
//
