ID G3PMX4_GASAC Unreviewed; 730 AA.
AC G3PMX4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Collagen, type VIII, alpha 1b {ECO:0000313|Ensembl:ENSGACP00000018957.1};
GN Name=COL8A1 {ECO:0000313|Ensembl:ENSGACP00000018957.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000018957.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000018957.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000018957.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3PMX4; -.
DR STRING; 69293.ENSGACP00000018957; -.
DR Ensembl; ENSGACT00000018995.1; ENSGACP00000018957.1; ENSGACG00000014373.1.
DR eggNOG; KOG3544; Eukaryota.
DR GeneTree; ENSGT00940000158272; -.
DR InParanoid; G3PMX4; -.
DR OMA; GNEMPHL; -.
DR TreeFam; TF334029; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000014373; Expressed in pharyngeal gill and 1 other cell type or tissue.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF903; COLLAGEN ALPHA-1(VIII) CHAIN; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 3.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..730
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003449720"
FT DOMAIN 597..730
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 38..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..147
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..258
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..563
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 71528 MW; 7078416D4D079B10 CRC64;
MAAAPLPPLC LPLVVLQLWS VHLAHGGAYY GHKLPPQQHQ PLPQYSDGYP QQQFLGNEMP
HLPYGKEVPL LPQYGKELPQ LPLQKGKGRP LIEGKGGEGL REGPQGVQGP PGTPGPPGPQ
GPPGLPGQGL PGLPGKTGPP GPQGYPGIGK PGVPGLPGKP GGPGLPGPKG ELGPYGGEGQ
TGLPGPPGLP GPPGLPGISK PGGQGLPGQL GPLGEPGTKG PPGFPGLPGP KGEKGHDQPG
LPGLKGPSGP PGPPGNVGIP GIGKPGFNGQ PGQQGVPGRP GAPGESGNAG PPGDRGQPGP
PGVPGIGKPG KDGLTGQSGP LGRKGESGPP GLPGGPGLPG YGKPGYPGPK GHNGHDGLHG
PPGLKGDKGH AGLPGVIGST GSSGRPGPPG PIGTPGSLGF PGQKGEDGVG GPKGYPGMKG
ELGPPGLPGQ PGSSAGGGQP GPRGLQGPIG PKGEPGIRGS PGAPGGAGLT GSRGEGGKPG
EKGYQGPQGI PGLTGPGGSL GPPGLPGPKG ETGLPGKPGY PGEGKPGPPG YIGPQGKPGP
SGPSGLPGHP GPPGLPGPPG LPAASPDLGQ ILPVTGPYTG QKQGYKKPKN GGNIGANGVE
MPAFTAELTN PFPLVGSPVV FDKLLYNGNQ NYNPQNGVFT CSVPGVYYFS YHVHCKGSNV
WVALMKNNEP VMYTYDEYKK GLLDQASGSA VLPLRQGDTV HIQLPSDQAA GLYAGQYVHS
TFSGYLLYPM
//
