ID G3PNH6_GASAC Unreviewed; 1258 AA.
AC G3PNH6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=KN motif and ankyrin repeat domains 1a {ECO:0000313|Ensembl:ENSGACP00000019159.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000019159.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000019159.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000019159.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3PNH6; -.
DR STRING; 69293.ENSGACP00000019159; -.
DR Ensembl; ENSGACT00000019197.1; ENSGACP00000019159.1; ENSGACG00000014520.1.
DR eggNOG; KOG0514; Eukaryota.
DR GeneTree; ENSGT00940000154886; -.
DR InParanoid; G3PNH6; -.
DR OMA; TFNPYLC; -.
DR TreeFam; TF324499; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000014520; Expressed in liver and 10 other cell types or tissues.
DR GO; GO:0030837; P:negative regulation of actin filament polymerization; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047184; KANK1-4.
DR InterPro; IPR021939; KN_motif.
DR PANTHER; PTHR24168; KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24168:SF19; KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF12075; KN_motif; 1.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 1067..1091
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1139..1171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1172..1205
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 820..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 881..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1235..1258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 416..450
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..918
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..939
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1258 AA; 134004 MW; 344D4E2A242A9832 CRC64;
MAQTMHVNGN GSERGQRCPS ADGEKDAAAP YYVETPYGYQ LDLDFLKYVD DIERGNTIKK
LSVHRKPKGA TPSTSGGGAP AEWTSTDSLS SSNSDDKQSP VFFGGGPQVA APLTPTLCRA
ACEAPQRPLL LPPPSPRFAP RHNPQVERTL METRLRLEQE RLLTQPPSLA SFGAGSSSSL
SSHSGSAGPS QISPGAPHPL PVNGHPPNGD YSLYYPSSMV SSIRHSPLSS GVATPVTNVS
PLHLQQIREQ MVVALRKLKE LEEQVKTIPI LQVKIAVLQE EKRQLAAQSK SQAAGSFRKR
SFSVGSAAQM EAPGAERQET ELHIMEPEAQ RQDAQRLDCA AEFRRLAAEV QALDGNAADA
RESQKSVGMV TDENMASLRA DQRARGPRSR DAAVSTERRE TRSAAVGVTE AMLGTSSEAE
REMELQQQTI ESLKEKIYRM EVQLKETTHQ LEMGKLKLEL QAAGGSGRKR VDKGSTARPE
TYDACVEARV QTRSVGAGEH LGPSTQSVAA GPETPMERWV VGVRVEVRDQ CVGREAGPSV
REAGVNTEES VDRLALCRPM AELSRESRSV GCGDCSVDVV VRPAKTLLSR GTDPERVGTA
DSAVTAAPES ATRQTNTETE VASKSTNTER SVRTDSSTDT GLLTCEKHTN TVGTDTRTVA
AGEGLVRDAH PAARGRTVAV GTGADAGSIL GGPAAARTRE CGVGPVSVQE NFLVGLKTRN
IASGPSQPSG SEGAVRVEDH YIERVQKLLQ EQQMLLAENY SELADAFGQP QSQFGSINCQ
LASTLSSINS VMKCGSAEDV LQLQRCDSLS QASGQQLCAG GRSQVEAPPA DRAAQQQVSA
AEQKSRMDLQ MSTALHGTAA ATTGGGGGRC LIPQSTLKSI MKKKDGRPDS NGTKKNLQFV
GVNGGYETTS SDDSSSEDSS SSGSDEEEDE DEKAFEGEEE YENVEARSVS EEFKPVGFRE
AGDEREVTEP CVSTRDPTNN KSIDCVHRYS LSEKMLSATN VLRAHLSDPK AVSSKDLRTC
INTVQHEWFR VSSQKSASAP MVGDYLAAFG AVSPAVLRHV VNMADGNGNT ALHYSVSHSN
FLVVKELLDA GEGGRGGKGA AGHTPIMLAA LAAVESPKDM RIVEELFSKG DVNARASQAG
QTGLMLAVSH GRMDMVRALL AQGADVNVQD DEGSTALMCA SEHGHVEIVK LLLARAGCDA
TLSDSDESNA LSIALEAGHK DIAMLLYAHV NFSKAQSPGT PRLSRKTSPS PTQRGVFD
//
