ID G3PTI1_GASAC Unreviewed; 1133 AA.
AC G3PTI1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Protogenin {ECO:0000313|Ensembl:ENSGACP00000020917.1};
GN Name=PRTG {ECO:0000313|Ensembl:ENSGACP00000020917.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000020917.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000020917.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000020917.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3PTI1; -.
DR STRING; 69293.ENSGACP00000020917; -.
DR Ensembl; ENSGACT00000020957.1; ENSGACP00000020917.1; ENSGACG00000015845.1.
DR eggNOG; KOG4221; Eukaryota.
DR GeneTree; ENSGT00940000155943; -.
DR InParanoid; G3PTI1; -.
DR OMA; MEDGYQA; -.
DR TreeFam; TF321506; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000015845; Expressed in embryo.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 5.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00060; FN3; 5.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 942..962
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..121
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 126..213
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 226..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 318..397
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 412..506
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 508..604
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 609..708
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 715..808
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 813..908
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1090..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1133 AA; 125406 MW; F37ABAD71BF53B6B CRC64;
MAPVERKLYQ RLLVFVAFLH ISGVLCFSEL FFIKEPHDVT VMRKEAVILD CQAHGESPID
VRWLKNGVKV VESERVYHLS NGSLYISEVE SRRGDKSDEG LYQCLAQNKY GAILSQKARL
TIASISAFAI QPTPAVVTEG SVARFSCKIS AHPPSIITWE FNRVTLPLTT ERITVLPSGV
LQIHRVQRAD AGNYRCISTN IASRRRSTEA TLTVFPAPRP QLPQRPRIIA GPQNISVSLH
QSAILECIAT GNPQPIISWS RADSKSIDVY STRVLGNGNL IITDIKPQHG GVYMCRATTP
GTRNYTVASA NITVLAPPSL VEWPESLTRP RAGTARFVCR AEGAPTPQIT WLKNGDKVHS
NGRIKMYNSK LVINQIIPED DAIYQCQAEN EQGSVLSMAR LIVVMSEDRP SAPRNIQADT
VSSSAILLAW ERPQYNSDKV IAYSVHYMKA EGLNNEEYQV VIGNDTTRYI IDDLEPARNY
TFYVVAYMPM GASRMSDNVF QHTLEDVPLR APELSLTSRS PMDIQVSWQP LPDKLSRGRV
SAYRLSYRTS SESTVSQIEL PGDKTQHFLE NLKPDTIYLL RIAAATSVGW GEQSVWTSHR
TPKTSSALVP MAPELRLEPL NCTAIVARWQ LAPRNSVSVQ GYRLFHHEES QSERSPVQLR
ALTNTYTFGG LDPRKKYHVK LLAYNFVGDG YQADQTISTP GCVSVRDRLV PPPPPPHNVY
TKTNSSTSVF LHWGRPAFTS SHAVNYTVRC NPVGLQNASL VLYLQTSEQN LLVTDLEPNT
KYEFAIRLHI DQLSSPWSPV VYQSTFPDAP TLPPSNVKVT LIEEDTALVS WKPPDEPNVA
VTHYTVLYAS RNAWIAGEWQ VLQREGTITM SLLEKLKPGQ IYFVKVSASN HMGDGPFSHT
MELTVQADFS SGHDPRLSHG STHPTGFSDG FYHLDQKSMT GITVGVCIAL ICIIICAFII
VCRGKNRKFS AAKKYGEGVN TSASVTAHLG SEGQAEQADV RIPVMSQNHF IDAKGGTNLV
INSLGPVRSC TEKKEKWFSF SSNGKKHSKA VQNMRHVSAS YQPGTPVLTF EDELSMSPDQ
PITLQALLWR PGDSEGSSNS EESHATGDSG RYSHDETEMT NLSSGTGSRP PSL
//
